首页|枯草杆菌二联活菌肠溶胶囊结合马来酸曲美布汀、心理干预治疗功能性腹泻的临床疗效观察

枯草杆菌二联活菌肠溶胶囊结合马来酸曲美布汀、心理干预治疗功能性腹泻的临床疗效观察

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目的 研究分析枯草杆菌二联活菌肠溶胶囊结合马来酸曲美布汀、心理干预治疗功能性腹泻的临床疗效观察.方法 选取杭州市红十字会医院2015年5月～2016年8月收治的100例功能性腹泻患者为研究对象,随机分为对照组和实验组,每组50例.对照组患者给予马来酸曲美布汀治疗,实验组患者给予枯草杆菌二联活菌肠溶胶囊结合马来酸曲美布汀、心理干预治疗,关注患者的心理状态,加强与患者的沟通和交流,增加患者的治疗信心和治疗依从性.比较分析实验组与对照组患者的治疗效果.结果 经过对应的治疗后实验组患者的治疗有效率为92.0％显著高于对照组84.0％,差异具有统计学意义(P<0.05).实验组与对照组患者均未见明显的不良反应.治疗后,实验组患者的腹泻(3.0±0.3)次显著少于对照组(4.3±0.3)次,差异具有统计学意义(P<0.05).结论 枯草杆菌二联活菌肠溶胶囊结合马来酸曲美布汀、心理干预治疗功能性腹泻临床效果较好,能够在很大程度上改善患者的临床症状,具有推广的意义.
Observation of clinical curative effect of Live Combined Bacillus Subtilis and Enterococcus Faecium Enteric-coated Capsules combined with trimebutine maleate and psychological intervention in the treatment of functional diarrhea
Objective To study the clinical efficacy of live combined bacillus subtilis and enterococcus faecium enteric-coated capsules combined with trimebutine maleate and psychological intervention in the treatment of functional diarrhea. Methods 100 patients with functional diarrhea treated in our hospital from May 2015 to August 2016 were selected and randomly divided into the control group and the experimental group, with 50 patients in each group. The control group were treated with trimebutine maleate treatment, the experimental group were treated with live combined bacillus subtilis and enterococcus faecium enteric-coated capsules trimebutine therapy and psychological intervention, pay attention to the psychological status of patients and patients, strengthen communication and exchanges, increase confidence in the treatment and the treatment compliance of patients. The therapeutic effects of the experimental group and the control group were compared and analyzed. Results After the corresponding treatment, the effective rate was 92.0％ in the experimental group and 84.0％ in the control group. The difference was statistically significant (P<0.05). There was no obvious adverse reaction in the experimental group and the control group. After treatment, the number of diarrhea in the experimental group was (3.0±0.3), significantly less than that of the control group (4.3±0.3), the difference was statistically significant (P<0.05). Conclusion The clinical effect of live combined bacillus subtilis and enterococcus faecium enteric-coated capsules combined with trimebutine maleate and psychological intervention in the treatment of functional diarrhea is good, can improve clinical symptoms in a large extent, has the meaning of promotion.

live combined bacillus subtilis and enterococcus faecium enteric-coated capsulestrimebutine maleatepsychological interventionfunctional diarrheaclinical curative effect

单彩云、杨静

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杭州市红十字会医院 消化内科,浙江 杭州 310000

枯草杆菌二联活菌肠溶胶囊 马来酸曲美布汀 心理干预 功能性腹泻 临床疗效

2017

10.3969/j.issn.1005-1678.2017.09.138

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN：1005-1678
年,卷(期)：2017.37(9)
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