轻度子宫内膜异位症伴不孕患者应用腹腔镜联合亮丙瑞林治疗的临床效果及对患者生育能力的影响
Clinical effect of laparoscopy combined with leuprorelin treatment on mild endometriosis and infertility and fertility function of patients
杨晓菁 1张埃姆1
作者信息
- 1. 杭州市妇产科医院 妇产科,浙江 杭州 310000
- 折叠
摘要
目的 探讨腹腔镜联合亮丙瑞林在轻度子宫内膜异位症伴不孕患者中的临床效果及对患者生育功能的影响.方法 取医院收治的轻度子宫内膜异位症伴不孕患者60例,随机数字法分为对照组(n=30)和观察组(n=30).对照组采用腹腔镜手术治疗,观察组联合亮丙瑞林治疗,采用全自动生化分析仪测定2组治疗前、后血清促卵细胞成熟素(follicle-stimulating hormone,FSH)、雌二醇(estradiol,E2)、促黄体生成素(luteinizing hormone,LH)和孕酮(progesterone,PROG)水平,采用妊娠率评估患者生育功能,比较2组临床疗效及对生育能力的影响.结果 观察组治疗后3个月FSH、E2、LH及PROG水平,均低于对照组,差异具有统计学意义(P<0.05);观察组治疗后1个月、2个月及3个月妊娠率,均高于对照组,差异具有统计学意义(P<0.05).结论 将腹腔镜联合亮丙瑞林用于轻度子宫内膜异位症伴不孕患者中效果理想,值得推广应用.
Abstract
Objective To investigate the clinical effect of laparoscopy combined with leuprolide on patients with mild endometriosis and infertility and effects on fertility function of patients. Methods A total of 60 patients with mild endometriosis and infertility in our hospital were randomly divided into the control group (n=30) and the observation group (n=30). The control group was treated with laparoscopic surgery, the observation group was treated with leuprorelin treatment, and the levels of FSH, E2, luteinizing hormone and PROG were tested by automatic biochemical analyzer between two groups before and after treatment, the pregnancy rate as assessment of reproductive function in patients. Clinical curative effect and effect on fertility of 2 groups were compared. Results Levels of FSH, E2, LH and PROG in the observation group were lower than those in the control group (P<0.05) in 3 months after treatment, and the pregnancy rates in the observation group after 1 months, 2 months and 3 months were higher than that in the control group (P<0.05). Conclusion The treatment of Laparoscopy combined with Leuprolide for mild endometriosis and infertility in patients has ideal effect, and is worthy of popularization and application.
关键词
腹腔镜/亮丙瑞林/轻度子宫内膜异位症/不孕/生育功能/临床效果Key words
Leuprolide/Laparoscopy/mild endometriosis/infertility/fertility function/clinical effect引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据