拜糖平与二甲双胍治疗2型糖尿病疗效及药物不良反应分析
Analysis of curative effect and drug adverse drug reaction in patients with type 2 diabetes treated by
付正进 1朱婵1
作者信息
- 1. 铜仁市人民医院门诊部 内科,贵州 铜仁 554300
- 折叠
摘要
目的 探讨拜糖平与二甲双胍治疗2型糖尿病的疗效及药物不良反应.方法 此次选择了2015年1月～2017年3月于本院诊治的2型糖尿病患者100例,随机将患者分为2组:对照组用二甲双胍治疗,观察组用拜糖平治疗;对2组患者治疗前后血糖控制情况、不良反应发生情况全面观察,将所获相关数据详细记录并作对比分析.结果 观察组患者空腹血糖、餐后2 h血糖、糖化血红蛋白改善程度优于对照组,差异有统计学意义(P<0.05);2组患者不良反应发生率比较,差异无统计学意义.结论 2型糖尿病患者选择拜糖平治疗效果显著,可有效改善患者空腹血糖、餐后2 h血糖、糖化血红蛋白,使患者临床症状得以改善,不良反应发生率低.
Abstract
Objective To investigate the efficacy and side effects of acarbose and metformin in the treatment of type 2 diabetes mellitus. Methods 100 patients with type 2 diabetes mellitus's choice of the January 2015 to March 2017 in our hospital, the patients were randomly divided into two groups: the control group was treated with metformin, acarbose treatment in observation group; the two groups before and after treatment of blood glucose control, the adverse reaction condition of comprehensive observation, will be granted the relevant data recorded and analyzed. Results Patients with fasting blood glucose, 2 h postprandial blood glucose, glycosylated hemoglobin improvement than the control group, the difference was statistically significant (P<0.05); two groups of patients with adverse reaction rate comparison, the difference was not statistically significant. Conclusion Patients with type 2 diabetes choose acarbose treatment effect significantly, can effectively improve the patients fasting blood glucose, 2 h postprandial blood glucose, glycosylated hemoglobin, clinical symptoms of patients can be improved, low incidence of adverse reactions.
关键词
拜糖平/二甲双胍/2型糖尿病/药物不良反应Key words
acarbose/Metformin/type 2 diabetes mellitus/adverse drug reactions引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据