晚期妊娠合并急性淋巴细胞性白血病1例
Acute lymphoblastic leukemia in third trimester of pregnancy:a case report
杨帆 1施鹏飞 1谢亚萍 1徐颖 1李沂玮 1钱申贤1
作者信息
- 1. 杭州市第一人民医院 血液内科,浙江 杭州 310000
- 折叠
摘要
目的 提高临床医生对妊娠合并急性白血病治疗的认识.方法 回顾性分析2016年12月13日本院收治的1例妊娠合并急性淋巴细胞性白血病患者的诊疗过程并讨论其终止妊娠时机的选择.结果 本例患者为28岁女性,停经32周+,确诊急性淋巴细胞性白血病,在地塞米松治疗2天后即行剖宫产一健康男婴,术后行常规化疗,治疗期间出现脑出血,手术病理明确有白血病中枢浸润,经抢救患者脱离生命危险,急性白血病完全缓解.结论 早期手术终止妊娠后再行化疗是晚期妊娠合并急性白血病治疗的可行方案.
Abstract
Objective To improve the understanding of clinician' treatment of pregnancy with acute lymphoblastic leukemia. Method To analyze tretrospectively the diagnosis and treatment process of 1 case with acute lymphoblastic leukemia from December 13, 2016, and discuss the selection of the timing of termination of pregnancy. Results The patient was a 28 years old female. She was dignosed for acute lymphocytic leukemia in the third trimester. She bore a healthy baby boy in caesarean section after a dexamethasone treatment for two days. Then she recevied a series of standard chemotherapy. But she suffered a cerebral hemorrhage during treatment, and surgical pathology made a definite dignosis of central nervous system leukemia.Finally, She was out of danger after rescue. Conclusion Postoperative chemotherapy is a feasible option for the treatment of acute leukemia after the termination of pregnancy.
关键词
急性淋巴细胞性白血病/妊娠/剖宫产术/化疗Key words
acute lymphoblastic leukemia/pregnancy/cesarean section/chemotherapy引用本文复制引用
基金项目
杭州市科技计划重点专病专科项目(20140733Q12)
出版年
2017
NETL
NSTL
维普
万方数据