首页|多种药物综合治疗急诊内科上消化道出血的效果分析

多种药物综合治疗急诊内科上消化道出血的效果分析

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目的 探讨急诊内科综合治疗上消化道出血的临床效果.方法 选取2014年6月~2016年10月本院急诊消化内科收治的上消化道出血患者102例为研究对象,随机分为观察组与对照组,各51例.对照组患者仅给予注射用艾司奥美拉唑钠、氨甲环酸治疗,观察组患者在对照组的基础上给予注射用矛头腹蛇血凝酶治疗.治疗结束后对2组患者的临床疗效进行评价,对比2组患者止血时间、住院天数、平均输血量、肠鸣恢复时间、腹痛缓解时间,并观察2组患者不良反应发生情况.结果 观察组患者的总有效率显著高于对照组(P<0.05);观察组患者的止血时间、住院天数及平均输血量均显著低于对照组(P<0.05);观察组患者肠鸣恢复时间与腹痛缓解时间显著低于对照组(P<0.05);观察组与对照组患者的不良反应发生率对比差异无统计学意义.结论 采用急诊内科综合治疗上消化道出血可显著提高临床疗效、缩短止血及恢复时间,值得临床推广应用.
Effect analysis of combined treatment with multiple drugs on upper gastrointestinal bleeding in emergency internal medicine
Objective To investigate the clinical effect of combined treatment of upper gastrointestinal bleeding in emergency internal medicine. Methods A total of 102 patients with upper gastrointestinal bleeding were enrolled in the Department of Emergency Gastroenterology, Peking Binhai University Hospital from June 2014 to October 2016. The patients were randomly divided into observation group and control group, 51 cases in each group.The control group were only given omeprazole sodium, tranexamic acid injection,the observation group were given Agkistrodon hemocoagulase for injection on patients on the basis of the control group.After treatment, the clinical curative effect of two groups of patients were evaluated, the hospitalization days, the average hemostasis time, blood transfusion, bowel recovery time, abdominal pain relief time, the adverse reactions occurred of the two groups were observed.Results The total effective rate of the observation group was significantly higher than that of the control group (P< 0.05). The hemostasis time,the time of hospitalization and the average blood transfusion in the observation group were significantly lower than those in the control group (P<0.05). The recovery time of bowel and the time of pain relief in the observation group were significantly lower than in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the observation group and the control group.Conclusion Comprehensive treatment of upper gastrointestinal bleeding with emergency internal medicine can significantly improve the clinical efficacy, shorten the time of hemostasis and recovery, and is worthy of clinical application.

emergency treatmentGI Medicinehemorrhage of upper digestive tractcombined treatmentclinical effect

孙蓉媛、杨万杰、孙莉萍、张柏文、徐英洁、张蕊

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天津市第五中心医院 急诊内科,天津 塘沽 300450

急诊 消化内科 上消化道出血 综合治疗 临床效果

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(9)
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