血清H-FABP、hs-CRP、cTnT三者联合检测对心肌梗死的诊断价值及临床分析
Diagnostic value and clinical analysis of combined detection of serum H-FABP, hs-CRP and cTnT in patients with myocardial infarction
戴小平1
作者信息
- 1. 浙江省缙云县钭氏伤科医院 检验科,浙江 丽水 321403
- 折叠
摘要
目的 分析血清心脏型脂肪酸结合蛋白(H-FABP)、超敏C反应蛋白(hs-CRP)、心肌肌钙蛋白T(cTnT)三者联合检测对心肌梗死的诊断价值.方法 选取2015年8月～2016年7月本院收治的50例心肌梗死患者视为A组,另选取48例因其他因素而导致的胸痛患者视为B组,同时选取53例在本院进行体检的无胸痛健康者视为C组.比较3组研究对象入院时H-FABP、hs-CRP、cTnT阳性情况,分析心肌梗死患者入院时5 h、10 h、24 h、3 d的H-FABP、hs-CRP、cTnT阳性情况.结果 A组的血清H-FABP、hs-CRP、cTnT阳性率显著高于B组、C组[82.00％(41/50)、68.00％(34/50)、76.00％(38/50)比8.33％(4/48)、14.58％(7/48)、10.42％(5/48)比0.00％(0/53)、0.00％(0/53)、0.00％(0/53)],差异具有统计学意义(P<0.05).在入院时5 h,H-FABP、hs-CRP的阳性率均高于入院时10 h、24 h、3 d的阳性率,在入院时10 h,cTnT的阳性率高于入院时5 h、24 h、3 d的阳性率,其中在入院5 h时的H-FABP阳性率显著高于入院3d时的阳性率(P<0.05).结论 联合检测血清H-FABP、hs-CRP、cTnT,能提高心肌梗死的诊断价值,并且能降低误诊率.
Abstract
Objective To evaluate the diagnostic value of serum cardiac fatty acid binding protein (H-FABP), high sensitivity C-reactive protein (hs-CRP) and cardiac troponin T (cTnT) in the diagnosis of myocardial infarction. Methods From August 2015 to July 2016, 50 patients with myocardial infarction were treated as group A, and 48 patients with chest pain caused by other factors were treated as group B, and 53 patients were selected in our hospital physical examination of patients without chest pain as C group. The levels of H-FABP, hs-CRP and cTnT were compared between the three groups. The levels of H-FABP, hs-CRP and cTnT in patients with myocardial infarction at 5 h, 10 h, 24 h and 3 d after admission were compared . Results The positive rate of serum H-FABP, hs-CRP and cTnT in group A was significantly higher than that in group B, group C[(82.00％, 41.00), 68.00％ (34/50), 76.00％ (38/50) VS 8.33％(4/48), 14.58％(7/48),10.42％(5/48) VS 0.00％(0/53),0.00％(0/53),0.00％(0/53)], and the difference was statistically significant (P<0.05). The positive rate of H-FABP and hs-CRP was higher than that of admission at 10 h, 24 h and 3 d at 5 h after admission. The positive rate of cTnT was higher than that at 5 h, 24 h and 3 d at admission (P<0.05). The positive rate of H-FABP was significantly higher than that of the control group (P<0.05). Conclusion Combined detection of serum H-FABP, hs-CRP and cTnT can improve the diagnostic value of myocardial infarction and reduce the misdiagnosis rate.
关键词
心脏型脂肪酸结合蛋白/超敏C反应蛋白/心肌肌钙蛋白T/心肌梗死Key words
heart-type fatty acid-binding protein/hypersensitive C-reactive protein/cardiac troponin T/myocardial infarction引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据