首页|孕妇妊娠不同时期血浆D-二聚体和凝血四项变化及其检验价值分析

孕妇妊娠不同时期血浆D-二聚体和凝血四项变化及其检验价值分析

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目的 对于孕妇妊娠不同时期血浆D-二聚体和凝血四项变化情况进行观察及分析,并且探究其检验的价值.方法 本研究对象是120例在江西省妇幼保健院进行常规体检的孕妇,依照不同的孕期阶段(妊娠早期、妊娠中期、妊娠后期、临产前),予以孕妇分别实施血浆D-二聚体、凝血四项的检测,观察并比较获得到的结果 情况.结果 在整个妊娠期间,D-二聚体具有进行性提升的趋势(P<0.05);在妊娠早期、妊娠中期、妊娠后期,PT具有缩短的情况,P<0.05;孕妇妊娠时,APTT具有缩短的情况(P<0.05),在妊娠后期至临产期阶段,呈现出显著的缩短现象(P<0.05);在妊娠早期至妊娠中期阶段,FIB显著提升(P<0.05),而且在妊娠后期至临产期时,具有急剧增加的情况(P<0.05).结论 对于孕妇妊娠期间实施动态的监测血浆D-二聚体、凝血四项指标具有重要意义,应该大力的推广实践.
Four changes of plasma D- dimer and coagulation in pregnant women at different stages of pregnancy and their value of test
Objective To observe and analyze the four changes of plasma D- dimer and coagulation in pregnant women at different stages of pregnancy, and to explore the value of the test. Methods The subjects of this study were 120 pregnant women who underwent routine physical examination in our hospital, according to different stages of pregnancy (early pregnancy, middle pregnancy, late pregnancy, and before delivery) Four D- dimer and four blood coagulation tests were performed in pregnant women, and the results were observed and compared. Results During the pregnancy, D- dimer has increase trend (P<0.05); early in pregnancy, pregnancy and late pregnancy, PT has shortened(P<0.05); pregnancy, APTT has shortened (P<0.05), at the end of pregnancy and parturient period, showing a significant shortening (P<0.05); phenomenon in early pregnancy to mid pregnancy stage, FIB increased significantly (P<0.05), and at the end of pregnancy to perinatal period, with a sharp increase (P<0.05). Conclusion It is of great significance to perform dynamic monitoring of of plasma D- dimer and coagulation four indices in pregnant women during pregnancy.

pregnancydifferent periodsplasma D- dimerblood coagulation fourtest value

曾辛、袁霞

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江西省妇幼保健院 检验科,江西 南昌 330006

江西省肿瘤医院 放疗科,江西 南昌 330006

妊娠 不同时期 血浆D-二聚体 凝血四项 检验价值

国家自然科学基金

81260103

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(9)
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