瑞芬太尼-氯胺酮在小儿静脉麻醉中的有效性和安全性探讨
Efficacy and safety of remifentanil ketamine in pediatric intravenous anesthesia
姜娜 1杨敏1
作者信息
- 1. 西北妇女儿童医院 麻醉科,陕西 西安 710061
- 折叠
摘要
目的 探讨瑞芬太尼-氯胺酮在小儿静脉麻醉中有效性和安全性.方法 对西北妇女儿童医院2015年4月~2017年4月收治的80例择期手术患儿的临床资料进行统计分析,依据静脉麻醉方法将这些患儿分为瑞芬太尼-氯胺酮组(40例)和丙泊酚-氯胺酮组(40例)2组,对2组患儿的血流动力学、麻醉药用量、苏醒时间、生活质量、副作用发生情况进行统计分析.结果 术中瑞芬太尼-氯胺酮组患儿的HR显著低于丙泊酚-氯胺酮组(P<0.05),术后瑞芬太尼-氯胺酮组患儿的麻醉药用量显著少于丙泊酚-氯胺酮组(P<0.05),苏醒时间显著短于丙泊酚-氯胺酮组(P<0.05),持续哭闹情况、疼痛感评分均显著低于丙泊酚-氯胺酮组(P<0.05),生理舒适度评分显著高于丙泊酚-氯胺酮组(P<0.05),副作用发生率7.5%(3/40)显著低于丙泊酚-氯胺酮组22.5%(9/40)(P<0.05).结论 瑞芬太尼-氯胺酮较丙泊酚-氯胺酮在小儿静脉麻醉中有效性和安全性高.
Abstract
Objective To explore the efficacy and safety of rifentani-ketamine in pediatric intravenous anesthesia. Methods In the northwest women's and children's hospital between April 2015 and April 2017 clinical data of 80 patients undergoing elective surgery patients in northwest women's and children's hospital were analyzed, on the basis of these children with intravenous anesthesia method divided into red fentanyl - ketamine group (40cases) and propofol ketamine group (40cases) in the two groups, the two groups of children with hemodynamics, drug dosage, wake up of time, quality of life and side effects happening for statistical analysis. Results Intraoperative red fentanyl ketamine group of HR was significantly lower than children with propofol - ketamine group (P<0.05), and postoperative fentanyl - children with dosage of anesthetic ketamine group was significantly less than the propofol - ketamine group (P<0.05), round time was significantly shorter than the propofol - ketamine group (P<0.05), the constant crying, pain scores were significantly lower than propofol - ketamine group (P<0.05), physical comfort score was significantly higher than that of propofol - ketamine group (P<0.05), the incidence of side effects of 7.5 % (3/40) was significantly lower than propofol - ketamine group 22.5 %(9/40) (P<0.05). Conclusion Rifentani-ketamine is more effective and safe in pediatric intravenous anesthesia, and is worth promoting in clinical practice.
关键词
瑞芬太尼-氯胺酮/小儿静脉麻醉/有效性/安全性Key words
rufentani-ketamine/pediatric intravenous anesthesia/effectiveness/security引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据