奥美拉唑联合克拉霉素治疗慢性胃炎的临床疗效分析
Clinical analysis of omeprazole combined with clarithromycin in the treatment of chronic gastritis
舒一民 1黄海聪 1尚才兵1
作者信息
- 1. 宁波市鄞州人民医院 急诊科,浙江 宁波 315040
- 折叠
摘要
目的 分析克拉霉素联合奥美拉唑的方案治疗慢性胃炎的临床效果.方法 选取2016年1月~2017年1月宁波市鄞州人民医院慢性胃炎患者100例,依据计算机随机原则分为对照组和观察组,每组50例.对照组给予奥美拉唑为主治疗,观察组在对照组治疗基础上联合使用克拉霉素治疗,对比2组治疗总有效率、复发情况、不良反应发生率等.结果 观察组慢性胃炎患者在治疗后,其治疗总有效率是90.00%,复发率是2.00%,各指标均得到良好改善,与对照组有效率(70.00%)和复发率(16.00%)相比,差异具有统计学意义(P<0.05).但2组不良反应发生率(8.00%vs 10.00%)对比差异无统计学意义.结论 在使用奥美拉唑的基础上,针对慢性胃炎患者联合实施克拉霉素的方案治疗,其效果更为理想.
Abstract
Objective To analyse the effect of clarithromycin omeprazole in patients with chronic gastritis after treatment. Methods 100 cases of chronic gastritis in Ningbo Yinzhou People's Hospital (January 2016 to January 2017) were selected and divided into 2 groups according to the principle of computer randomization. One group was treated with omeprazole (control group) and the other group was treated with clarithromycin (observation group). Comparison of the total effective rate of 2 groups, relapse, the occurrence of adverse reactions and so on. Results In the observation group, the total effective rate was 90.00% and the recurrence probability was 2.00 % after treatment. The indexes were improved, compared with the control group (70.00 % and 16.00 %, respectively) Dominant position (P<0.05). However, the probability of adverse events in the two groups was not significantly different, which was 8.00% vs 10.00 %. Conclusion The use of omeprazole on the basis of the treatment of patients with chronic gastritis and then combined with the treatment of clarithromycin, the effect is more ideal.
关键词
奥美拉唑/克拉霉素/慢性胃炎/复发Key words
omeprazole/clarithromycin/chronic gastritis/relapse引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据