首页|鞘内注射头孢他啶与头孢曲松治疗脑室外引流术后颅内感染60例

鞘内注射头孢他啶与头孢曲松治疗脑室外引流术后颅内感染60例

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目的 探究鞘内注射头孢他啶与头孢曲松治疗脑室外引流术后颅内感染的临床效果.方法 选取2013年10月~2017年3月宁夏医科大学附属吴忠市人民医院神经外科收治的60例脑室外引流术后颅内感染患者,随机抽签分类法分为参照组和研究组,每组30例.参照组采用头孢曲松治疗,研究组采用鞘内注射头孢他啶与头孢曲松治疗,评估2组患者的治疗效果以及不良反应发生率.结果 研究组患者的治疗总有效率(96.67%)显著高于参照组(73.33%);不良反应发生率(3.33%)明显低于参照组(26.66%),差异均有统计学意义(P<0.05).结论 采用鞘内注射头孢他啶与头孢曲松治疗脑室外引流术后颅内感染患者,治疗效果显著,不良反应发生率较低.
Intrathecal injection of ceftazidime and ceftriaxone in the treatment of 60 cases of intracranial infection after intraventricular drainage
Objective To investigate the clinical effect of intrathecal injection of ceftazidime and ceftriaxone in the treatment of intracranial infection after intraventricular drainage. Methods 60 patients with intracranial infection after intraventricular drainage in Wuzhong people's hospital from October 2013 to March 2017 were selected and were divided into reference group and study group by random sampling method, with 30 cases in each group. The reference group was treated with ceftriaxone treatment, the study group was treated with intrathecal ceftazidime and ceftriaxone. The therapeutic effect and adverse reaction rate of the two groups were evaluated. Results The total effective rate of the patients in the study group (96.67%) was significantly higher than that in the reference group (73.33 %), and the adverse reaction rate (3.33%) was significantly lower than that of the reference group (26.66%), and the difference was statistically significant (P<0.05). Conclusion Intrathecal injection of ceftazidime and ceftriaxone in patients with intracranial infection after intraventricular drainage, the treatment effect is obvious, and the incidence of adverse reactions is low, which is worthy of clinical study.

intrathecal injectionceftazidimeceftriaxoneintracranial infectionintraventricular drainage

文志刚、耿灵军

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宁夏医科大学附属吴忠市人民医院 神经外科,宁夏 吴忠 751100

鞘内注射 头孢他啶 头孢曲松 脑室外引流术 颅内感染

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(10)
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