首页|补阳还五汤联合沙格雷酯治疗老年性糖尿病合并下肢动脉硬化闭塞症患者的效果观察

补阳还五汤联合沙格雷酯治疗老年性糖尿病合并下肢动脉硬化闭塞症患者的效果观察

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目的 观察补阳还五汤联合沙格雷酯治疗老年糖尿病合并下肢动脉硬化闭塞症(ASO)患者的效果.方法 选取2014年12月~2016年12月浙江省立同德医院接受治疗的102例糖尿病合并下肢ASO患者,按治疗方式分为实验组和对照组,每组51例.对照组接受沙格雷酯治疗,实验组基于对照组联合补阳还五汤治疗,2组均持续用药2个月.比较并观察2组临床疗效、足背动脉血流量、踝肱指数、跛行距离及不良反应发生情况.结果 实验组总有效率92.16%高于对照组76.47%(P<0.05).实验组足背动脉血流量、踝肱指数、跛行距离高于对照组(P<0.05).2组不良反应差异无统计学意义.结论 补阳还五汤联合沙格雷酯治疗老年糖尿病合并下肢ASO患者的效果肯定,能有效促进患者恢复.
Observation of effects of buyang huanwu decoction combined with sarpogrelate hydrochloride in the treatment of elderly diabetes mellitus complicated with lower extremity arteriosclerosis obliterans
Objective To observe the effects of buyang huanwu decoction combined with sarpogrelate hydrochloride in the treatment of elderly diabetes mellitus associated with lower extremity arteriosclerosis obliterans(ASO). Methods 102 patients with diabetic lower limb ASO enrolled in Tongde hospital from December 2014 to December 2016 were divided into the experimental group and the control group according to the treatment way, with 51 cases in each group. The control group was treated with sarpogrelate hydrochloride, the experimental group was treated with buyang huanwu decoction based on the basis of control group, both groups was treated for two months. The clinical curative effect, the dorsalis pedis artery blood flow, ankle brachial index, claudication distance, and adverse reactions occur was compared and observed between two groups. Results The total effective rate of the experimental group was 92.16% higher than 76.47% of the control group (P<0.05). The dorsalis pedis artery blood flow, ankle brachial index, claudication distance of experimental group was higher than the control group (P<0.05). There was no significant difference in adverse reactions between the two groups. Conclusion The effect of buyang huanwu decoction joint sarpogrelate hydrochloride in the treatment elderly diabetes ASO, can relieve body blood, blood fat, blood sugar state, promote patient recovery.

elderly diabetes mellituslower extremity arteriosclerosis obliteransBuyang huanwu decoctionsarpogrelate hydrochloride

周叶娜

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浙江省立同德医院 乳甲肝胆血管外科,浙江 杭州 310012

老年糖尿病 下肢动脉硬化闭塞症 补阳还五汤 沙格雷酯

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(10)
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