摘要
目的 分析益肾康胶囊对慢性肾炎尿毒症患者尿蛋白的影响.方法 选取温州医科大学附属第二医院2013年3月~2016年4月收治的100例慢性肾炎尿毒症患者,抽签法分为治疗组和对照组,各50例,2组均接受透析以及常规治疗,治疗组另给予益肾康胶囊,分析2组尿蛋白变化.结果 治疗后,2组24 h尿蛋白较治疗前下降,白蛋白(Albumin,Alb)和血红蛋白(Hemoglobin,Hb)均较治疗前上升,治疗组均优于对照组,2组比较差异具有统计学意义(P<0.05).2组血肌酐(Serum creatinine,SCr)、血尿素(Blood urea nitrogen,BUN)和尿酸(Uric acid,UA)水平均较治疗前下降,治疗组均低于对照组,2组比较差异具有统计学意义(P<0.05).治疗后,对照组炎症水平较治疗前略上升,治疗组下降,且均低于对照组,2组比较差异具有统计学意义(P<0.05).治疗期间,组间各不良反应差异均无统计学意义.结论 益肾康胶囊可降低慢性肾炎尿毒症患者尿蛋白排泄,改善肾功能,不良反应少.
Abstract
Objective To analyze the effect of Yishenkang capsule on urinary protein in patients with chronic glomerulonephritis uraemia. Methods 100 patients with chronic glomerulonephritis uraemia from March 2013 to April 2016 were divided into two groups with lottery method and 50 cases for each group. Two groups were treated with dialysis and routine treatment, the treatment group was added Yishenkang capsule to analyze its effect. Results After treatment, 24 h urinary protein of two groups decreased than before treatment, both Alb and Hb increased than before treatment, and the treatment group was better than that of the control group with statistical significance (P<0.05). SCr, BUN and UA level of two groups decreased than before treatment, the treatment group was lower than that of the control group with statistical significance (P<0.05). The level of inflammation in the control group was significantly higher than that before treatment, the treatment group decreased and lower than that of the control group with statistical significance (P<0.05). There were no significant differences in adverse reactions between two groups. Conclusion Yishenkang capsule could decrease the excretion of urine protein in patients with chronic nephritis uraemia, improve the renal function and has few adverse reactions.
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维普
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