芪蝎活血通络汤联合奥扎格雷钠治疗脑血栓形成及改善脑缺血再灌注损伤的效果分析
Effect of Qixie Huoxue Tongluo decoction combined with ozagrel in treatment of cerebral thrombosis and cerebral ischemia reperfusion injury
张万红1
作者信息
- 1. 千阳县人民医院 神经内科,陕西 咸阳 721100
- 折叠
摘要
目的 分析芪蝎活血通络汤联合奥扎格雷钠治疗脑血栓形成及对改善脑缺血再灌注损伤的效果.方法 选取2015年4月~2016年4月来千阳县人民医院就诊的脑血栓患者106例,平均分成对照组和观察组,每组53例.对照组患者采用奥扎格雷钠再灌注进行治疗,观察组采用芪蝎活血通络汤联合奥扎格雷钠进行治疗.2组患者接受治疗后,对其临床效果进行对比.结果 2组患者接受为期1 w的治疗之后,观察组患者机体炎症因子(hs-CRP、TNF-α等)含量均比观察组低(P<0.05);NIHSS及ADL评分情况比对照组患者高(P<0.05);观察组患者不良反应情况低于对照组(P<0.05);观察组临床治疗有效比率高于对照组(P<0.05).结论 芪蝎活血通络汤联合奥扎格雷钠对于脑血栓患者有很好的治疗效果,对于脑缺血再灌注损伤也有一定的改善.
Abstract
Objective To evaluate the effect of Qixuoxue Huoxue Tongluo decoction combined with ozagrel sodium on cerebral thrombosis and to improve cerebral ischemia-reperfusion injury. Methods 106 patients of cerebral thrombosis from April 2015 to April 2016 were divided into control group and observation group, each group of 53 patients. The patients in the control group were treated with ozagrel sodium for reperfusion. The observation group was treated with Qixiqi Huoxue Tongluo decoction and ozagrel sodium for treatment. Resulrs The levels of inflammatory factors (hs-CRP, TNF-α, etc.) in the observation group were lower than those in the observation group (P<0.05), and the two groups were compared with the observation group (P<0.05). The adverse effects of NIHSS and ADL were higher than those of the control group (P<0.05). The adverse effects of NIHSS and ADL were significantly lower than those of the control group (P<0.05) ; Conclusion Qixie Huoxue Tongluo Decoction combined with ozagrel sodium for cerebral thrombosis patients have a good therapeutic effect, for cerebral ischemia and reperfusion injury also have some improvement.
关键词
芪蝎活血通络汤/奥扎格雷钠/脑血栓/脑缺血再灌注损伤Key words
Qingxiehuoxue Huoxue Tongluo decoction/ozagrel sodium/cerebral thrombosis/cerebral ischemia-reperfusion injury引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据