首页|介入治疗与药物治疗在脑梗死患者中的疗效对比及对凝血功能的影响

介入治疗与药物治疗在脑梗死患者中的疗效对比及对凝血功能的影响

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目的 探讨介入治疗与药物治疗在脑梗死患者中的临床效果及对机体凝血功能的影响.方法 选取2016年4月~2017年6月收治的92例脑梗死患者作为研究对象,经单双数字法(入院就诊顺序)随机均分为研究组(n=46)和对照组(n=46).研究组脑梗死患者接受介入手术治疗,对照组脑梗死患者实施药物保守治疗,记录2组治疗效果、凝血功能变化情况.结果 治疗后2组NIHSS量表评分均较之前显著下降(P<0.05),但2组间的差异无统计学意义;研究组治疗前后APTT、PT、FIB等凝血功能指标并未出现显著变化,对照组治疗后上述凝血功能相关指标均较治疗前发生显著改变(P<0.05).结论 临床医生需根据患者实际情况准确选择相应治疗方案,从而有利于保障脑梗死治疗有效性、安全性.
Comparative observation on the effect of interventional therapy and drug therapy on the treatment of the patients with cerebral infarction and the influence on coagulation function
Objective To investigate the clinical effect of interventional therapy and drug therapy on the treatment of the patients with cerebral infarction and the influence on coagulation function. Methods A total of 92 patients with cerebral infarction from April 2016 and June 2017 were randomly divided into the study group (n=46) and the control group (n=46) by single and double digit method. The study group were treated with interventional therapy, and the control group were treated with drug conservative treatment. The effect and coagulation function in the two groups were recorded and compared. Results After treatment, NIHSS scale scores in the two groups were decreased significantly than before (P<0.05), the difference between the two groups has no statistically significant; There were no significant changes in the levels of APTT, PT and FIB before and after treatment in the study group. Compared with pre-treatment, there were significant changes in the levels of APTT, PT, FIB in the control group (P<0.05). Conclusion Clinicians should select the appropriate treatment program according to the actual situation of patients, so as to ensure the effectiveness and safety of the patients with cerebral infarction.

ICU cerebral infarctioninterventional treatmentdrug treatmentcoagulation function

施王慧、施文君

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杭州市余杭区第一人民医院 检验科,浙江 杭州 311100

上海长海医院 内分泌科,上海 200433

ICU 脑梗死 介入治疗 药物治疗 凝血功能

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(10)
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