首页|骨康胶囊联合透明质酸钠局部注射治疗骨性关节炎的疗效及安全性

骨康胶囊联合透明质酸钠局部注射治疗骨性关节炎的疗效及安全性

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目的 探讨骨康胶囊联合透明质酸钠局部注射治疗骨性关节炎的临床应用效果和安全性.方法 选取永康市骨科医院于2015年12月~2017年3月期间收治的94例骨性关节炎患者作为研究对象,利用随机数字表法随机均分为研究组(n=47)和对照组(n=47).对照组患者给予透明质酸钠局部注射,研究组给予透明质酸钠局部注射联合骨康胶囊治疗.记录并比较2组治疗前后膝关节功能(HSS量表评分)变化情况、不良反应发生率.结果 治疗前2组患者HSS量表评分对比,差异无统计学意义;治疗后研究组HSS量表评分显著优于对照组(P<0.05);治疗期间2组各项不良反应发生情况对比差异无统计学意义.结论 在透明质酸钠局部注射治疗骨性关节炎基础上,加用骨康胶囊可显著提高疗效,安全性较高.
Observation on the efficacy and safety of Gukang capsule combinedwithsodium hyaluronate injection on the treatment of the patients with osteoarthritis
Objective To investigate the effect and safety of Gukang capsule combined with sodium hyaluronate injection on the treatment of the patients with osteoarthritis. Methods 94 osteoarthritis patients selected from December 2015 to March 2017 were randomly divided into study group (n=47) and control group (n=47). The control group were given sodium hyaluronate injection, the study group were received local injection of sodium hyaluronate combined with Gukang capsule. The changes of knee joint function (HSS scale score) and adverse reaction rate were recorded and compared before and after treatment in the two groups. Results Before treatment, there was no significant difference in HSS scores between the two groups. After treatment, the HSS score in the study group was significantly better than that in the control group (P<0.05). There were no significant differences in the adverse reactions between the 2 groups during the treatment. Conclusion Local injection of sodium hyaluronate combined with Gukang capsule on the treatment of osteoarthritis, which can significantly improve the clinical efficacy, the security is higher. .

osteoarthritisGukang capsulesodium hyaluronatesafety

吕新建、于小中、李继川、吕鹏起、项风

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永康市骨科医院 骨科,浙江 永康 321300

骨性关节炎 骨康胶囊 透明质酸钠 安全性

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(10)
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