贞芪扶正颗粒对慢性粒细胞白血病化疗患者免疫指标的影响
Effects of Zhenqifuzheng grain on immune function of patients with chronic myeloid leukemia during chemotherapy
王海霞 1王鑫昱 2周燕红2
作者信息
- 1. 杭州市丁桥医院 药剂科,浙江 杭州 310024
- 2. 杭州市中医院,浙江 杭州 310007
- 折叠
摘要
目的 分析贞芪扶正颗粒对慢性粒细胞白血病化疗患者免疫指标的影响.方法 选取2012年1月~2015年12月本院血液科收治的94例慢性粒细胞白血病患者,随机数字表法分成2组,各47例.2组均进行化疗,观察组另服用贞芪扶正颗粒.结果 化疗后,观察组WBC、Hb、PLT水平、免疫指标均优于对照组(均P<0.05),观察组KPS评分高于对照组(P<0.05).化疗期间,观察组胃肠道反应和肝肾功能损伤的比例分别低于对照组(P<0.05).结论 贞芪扶正颗粒可改善慢性粒细胞白血病化疗患者免疫功能,可降低不良反应.
Abstract
Objective To analyse effects of Zhenqifuzheng grain on immune function of patients with chronic myeloid leukemia during chemotherapy. Methods 94 patients with chronic myeloid leukemia from January 2012 to December 2015 were randomly divided into 2 groups, each with 47 cases. Two groups were treated with chemotherapy and observation group was treated another with Zhenqifuzheng grain. Results After chemotherapy, WBC, Hb, PLT level, immune index and KPS score of observation group were better than that of control group(P<0.05).During chemotherapy, gastrointestinal reaction and liver function damage proportion of observation group were lower than that of control group (all P<0.05). Conclusion Zhenqifuzheng grain can improve immune function of patients with chronic myeloid leukemia during chemotherapy and reduce adverse reaction.
关键词
贞芪扶正颗粒/慢性粒细胞白血病/化疗/免疫指标Key words
Zhenqifuzheng grain/chronic myeloid leukemia/chemotherapy/immune function引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据