培美曲塞二钠和卡铂联合心理干预治疗老年中晚期非小细胞肺癌的临床作用
Clinical observation of pemetrexed disodiun, carboplatin and psychological intervention in the treatment of elderly patients with advanced non-small cell lung cancer
吕娟妹 1姚春瑜1
作者信息
- 1. 海宁市人民医院 呼吸二科,浙江 海宁 314400
- 折叠
摘要
目的 探讨培美曲塞二钠和卡铂联合心理干预治疗老年中晚期非小细胞肺癌中的临床效果.方法 选取海宁市人民医院2015年2月~2017年2月收治的92例老年中晚期非小细胞肺癌患者,经单双数字法(入院就诊顺序)将患者随机均分为研究组(n=46)和对照组(n=46).对照组给予卡铂、培美曲塞二钠联合治疗,研究组给予卡铂、培美曲塞二钠、心理干预联合治疗,记录2组老年中晚期非小细胞肺癌患者近期疗效.结果 研究组临床总有效率高达67.39%,对照组临床总有效率仅为47.83%,数据对比差异具有统计学意义(P<0.05),提示研究组老年中晚期非小细胞肺癌患者临床疗效更优.结论 对老年中晚期非小细胞肺癌患者给予培美曲塞二钠、卡铂、心理干预联合治疗可显著提高其临床疗效,对保障患者生活质量、生命安全具有积极意义.
Abstract
Objective To investigate the clinical efficacy of pemetrexed disodium, carboplatin and psychological intervention in the treatment of elderly patients with advanced non-small cell lung cancer. Methods 92 cases of elderly patients with advanced non-small cell lung cancer from February 2015 to February 2017 were randomly divided into study group (n=46) and control group (n=46) by the single and double number (hospital admission order).The control group was treated with carboplatin and pemetrexed disodium treatment, the study group was treated with carboplatin and pemetrexed disodium, combined with psychological intervention treatment, effects of treatment in elderly patients with advanced non-small cell lung cancer between two groups were recorded. Results The total effective rate of the study group (67.39%) was significantly higher than the control group (47.83%)with statistical significance (P<0.05), it suggested that the clinical efficacy of the study group in elderly patients with advanced non-small cell lung cancer is better. Conclusion The application of pemetrexed disodium, carboplatin, combined with psychological intervention treatment for elderly patients with advanced non-small cell lung cancer patients could significantly improve clinical efficacy, has positive significance to guarantee the quality of life of patients and life safety.
关键词
中晚期非小细胞肺癌/培美曲塞二钠/卡铂/心理干预Key words
medium and advanced non-small cell lung cancer/pemetrexed disodium/carboplatin/psychological intervention引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据