首页|护理干预联合盐酸多奈哌齐治疗老年痴呆的疗效观察

护理干预联合盐酸多奈哌齐治疗老年痴呆的疗效观察

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目的 分析护理干预联合盐酸多奈哌齐治疗老年痴呆的疗效观察.方法 选取2015年2月~2016年8月收治100例老年痴呆患者为研究对象,随机分为对照组和实验组,各50例.对照组患者给予盐酸多奈哌齐治疗,实验组在此基础上进行护理干预措施,制定合理护理方案,提供舒适医疗环境,给予针对性安全护理和心理护理.比较2组患者的临床疗效.结果 治疗后,实验组治疗有效率为94.0%,显著高于对照组有效率76.0%,差异具有统计学意义(P<0.05).治疗后,实验组患者MMSE与ADL评分分别为(22.30±3.12)和(62.33±11.45)显著优于对照组,差异具有统计学意义(P<0.05).2组患者不良反应发生率分别为10.0%和12.0%,差异无统计学意义.结论 护理干预联合盐酸多奈哌齐治疗老年痴呆临床疗效较为理想,能够显著改善患者认知能力,安全性较高.
Efficacy of nursing intervention combined with donepezil in the treatment of senile dementia
Objective To investigate and analyze the efficacy of nursing intervention combined with donepezil in the treatment of senile dementia. Methods 100 patients with Alzheimer's disease from February 2015 to August 2016 in our hospital were randomly divided into the control group and the experimental group, with 50 cases in each group. The patients in control group were treated with donepezil hydrochloride, and the experimental group was given nursing intervention measures, reasonable nursing program, comfortable medical environment, targeted safety nursing and psychological nursing were given. The clinical efficacy of the two groups was compared. Results After treatment, the effective rate of the experimental group was 94.0%, which was significantly higher than that of the control group, and the effective rate was 76.0%, the differences were statistically significant(P<0.05). After treatment, the scores of MMSE and ADL in the experimental group were (22.30±3.12) and (62.33±11.45) significantly better than that of the control group, the differences were statistically significant(P<0.05). The incidence of adverse reactions in the two groups was 10% and 12%, respectively, and there was no statistical significance. Conclusion The clinical efficacy of nursing intervention combined with donepezil in the treatment of senile dementia is ideal, can significantly improve the cognitive ability of patients, and has high security.

nursing interventiondonepezil hydrochlorideAlzheimer's disease

余娜

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浙江省金华市第二医院 老年五科,浙江 金华 321025

护理干预 盐酸多奈哌齐 老年痴呆

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(10)
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