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异甘草酸镁对肝切除术后患者的保肝作用与护理干预

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目的 分析异甘草酸镁对肝切除术后患者的保肝作用与护理干预.方法 选取丽水市中心医院64例进行肝切除术患者为研究对象,随机分为对照组和实验组,每组32例.对照组手术开始给予150 mg异甘草酸镁,术后连续用药7 d.实验组在此基础上进行针对性护理干预,关注患者心理状态,耐心为患者讲解,做好术前准备,密切观察患者肝功能相关指标.比较分析2组患者相应临床指标.结果术后7 d,实验组ALT水平为(50.20±23.21)U/L,AST水平为(25.40±9.03)U/L.对照组ALT水平为(95.43±43.90)U/L,AST水平为(38.33±9.19)U/L,2组患者比较差异具有统计学意义(P<0.05).2组患者均未出现明显不良反应,差异不具有统计学意义.术后实验组血清ALT水平降到正常范围例数显著多于对照组,差异具有统计学意义(P<0.05).结论 异甘草酸镁与护理干预对肝切除术后的保肝作用较为理想,能够显著改善患者肝功能,安全性高.
Protective effect and nursing intervention of magnesium magnesium oxalate on liver function after hepatectomy
Objective To study the protective effect of nursing intervention and magnesium oxalate on liver function after hepatectomy. Methods 64 cases of liver resection patients in our hospital were randomly divided into the control group and the experimental group, with 32 patients in each group. In the control group, patients were given 150mg magnesium magnesium sulfate for 7 days after the operation. On this basis treatment of the control group, the experimental group was carried out targeted nursing intervention, payed attention to the patient's psychological state, patiently explain to the patients, did well preoperative preparation, and closely observed the correlation of liver function. Clinical indicators of the two groups of patients were compared and analyzed. Results 7 days after operation, the level of ALT in the experimental group was (50.20±23.21) U/L, and the level of AST was (25.40±9.03) U/L. The level of ALT in the control group was (95.43±43.90) U/L, and the level of AST was (38.33 ± 9.19) U/L, there were statistical significance in two groups (P<0.05). There were no obvious adverse reactions in two groups, and there was no statistical significance (P<0.05). The level of serum ALT in the experimental group decreased to normal range, and the number of patients was significantly higher than that of the control group with statistical significance (P<0.05). Conclusion The effect of Magnesium Oxalate and nursing intervention on liver function after hepatectomy is ideal. It can significantly improve the liver function of patients with high safety and clinical significance.

nursing interventionMagnesium Oxalatehepatectomyliver protection effect

林巧琴、吴曙霞

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丽水市中心医院 肝胆胰外科,浙江 丽水 323000

护理干预 异甘草酸镁 肝切除术 保肝作用

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(10)
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