Clinical value of serum glycosylated hemoglobin and N-terminal brain natriuretic peptide in patients with acute coronary syndromes
Objective To investigate the significance of serum HbA1c and N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with acute coronary syndromes. Methods 120 patients with acute coronary syndromes were enrolled in Jinhua Wenrong hospital from June 2015 to December 2016. Among them, 68 patients with diabetes mellitus (group A) and 52 patients without diabetes (group B) were selected. 80 healthy cases in this hospital were selected as the control group. (HbA1c) and N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured and compared. Results The level of serum HbA1c in group A was (9.52±1.57)%, which was significantly higher than that in group B (5.92±0.36)%, control group (5.82±0.41)%, t=(16.19, 20.29), P=(0.00, 0.00); And group B compared with the control group, t=1.43, P=0.15. The level of NT-proBNP in group A was (442.78±79.14) μg/mL, which was significantly higher than that in group B (221.45±33.89) μg/mL, control group (87.14±14.82) μg/mL, t=(18.87, 39.41), P= (0.00, 0.00); and group B was significantly higher than those in the control group, t=31.19, P=0.00. Cardiac function in patients with acute coronary syndromes was positively correlated with serum HbA1c and NT-proBNP (r=0.624, 0.582). Conclusion The levels of HbA1c and NT-proBNP in patients with acute coronary syndromes were significantly higher than those in patients with acute coronary syndromes. The levels of HbA1c and NT-proBNP in patients with acute coronary syndromes were helpful to evaluate their cardiac function.
glycosylated hemoglobincoronary heart diseaseacute coronary syndromeN-terminal brain natriureticcardiac function
NETL
NSTL
万方数据
维普
