首页|缩宫素联合欣母沛在瘢痕子宫产后出血及憩室中的预防效果

缩宫素联合欣母沛在瘢痕子宫产后出血及憩室中的预防效果

Prevention of postpartum hemorrhage and diverticulum in scarred uterus with oxytocin and hemabate

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目的 探讨缩宫素联合欣母沛在瘢痕子宫产后出血及憩室中的预防效果.方法 随机选择陕西省西安市长安医院于2016月5月~2017年5月期间收治的瘢痕子宫产后出血及憩室产妇88例作为研究对象,通过对产妇编号和随机分组分为2组,每组各44例,其中对照组采用缩宫素治疗,观察组则采用缩宫素联合欣母沛治疗,对治疗后2组产妇的术中出血量、术后2 h出血量、产后24 h出血量、不良反应发生情况进行比较分析.结果 观察组产妇术中出血量、术后2 h出血量、产后24 h出血量与对照组相比,均明显偏低,差异具有统计学意义(P<0.05);观察组产妇产后出血率(6.81%)明显低于对照组产后出血率(27.27%),差异具有统计学意义(P<0.05);观察组产妇恶心呕吐、心率加快、血压升高等不良反应发生率显著低于对照组(4.54%vs.18.18%),差异具有统计学意义(P<0.05).结论 在瘢痕子宫产后出血及憩室中应用缩宫素联合欣母沛治疗具有明显的疗效,是减少出血量和保证安全性的重要手段.
Objective To investigate the efficacy of oxytocin combined with hemabate in the prevention of postpartum hemorrhage and diverticulum in scarred uterus. Methods 88 patients with scar uterus, postpartum hemorrhage and diverticulum in Chang'an Hospital from May 2016 to May 2017 were divided into two groups by maternal numbering and randomization, with 44 patients in each group. The control group was treated with oxytocin, and the observation group was treated with oxytocin combined with hemabate. It must compare the amount of bleeding, the amount of 2 h bleeding, the amount of postpartum 24 h bleeding and the incidence of adverse reactions in the two groups after the treatment. Results Compared with the control group, the amount of bleeding, the amount of two hours' bleeding and the amount of postpartum 24 hours' bleeding in the observation group were significantly lower than that in the control group(P<0.05). The postpartum hemorrhage volume of the observation group was 6.81%, which was lower than that of the control group, and the rate of postpartum hemorrhage was 27.27% (P<0.05). The incidence of adverse reactions such as nausea, vomiting, heart rate and blood pressure in the observation group was significantly lower than that in the control group (4.54% vs. 18.18%), the difference was statistically significant(P<0.05). Conclusion In the scar uterus, postpartum hemorrhage and diverticulum, the use of oxytocin combined with hemabate treatment has obvious curative effect. It is an important measure to reduce the amount of bleeding and ensure safety.

oxytocinhemabatescar uterusuterine diverticulum

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陕西省西安市长安医院 妇科,陕西 西安 710016

缩宫素 欣母沛 瘢痕子宫:子宫憩室

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(10)
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