Optical coherence tomography technic for mucous membrane structure in larynx
Objective To discuss the feasibility and possibility of optical coherence tomography (OCT) technic for mucous membrane in larynx and voice science. Methods Three ex-vivo larynxes which were excised due to laryngeal carcinoma were examined by the optical coherence tomography, and then were compared with the same pathological sections. Results OCT images of larynx mucous membrane include epiglottis, vocal folds, false vocal folds, laryngeal ventricle, anterior commissure, and laryngeal carcinoma were obtained. The differences of microstructure between the normal tissue and laryngeal carcinoma could be clearly identified by OCT. Conclusion OCT is a non-invasive, high-speed, real-time technic for larynx mucous membrane structure, especially for the vocal folds epithelium and superficial lamina propria, and is possible for voice science.