Expressions and clinical significance of VEGF and CYP1A1 in non-mall cell lung cancer
Objective To explore the relationship between VEGF and CYP1A1 and the development and progression of lung cancer. Methods 58 cases of lung cancer tissue and 16 cases of normal tissue were detected by Max vision immunohistochemistry. Results Immunohistochemistry results show: compared with adjacent normal group,there was significant difference in the positive rate ofCYP1A1 and VEGF in lung cancer group (P<0.05). The positive expression rates of CYP1A1 and VEGF were significantly different between stage I, II andIII, IV (P<0.05). The correlation coefficient of VEGF and CYP1A1 was 0.723. Conclusion VEGF and CYP1A may be associated with the occurrence and development of tumor. Correlation coefficient indicated the positive correlation between VEGF and CYP1A1expression