首页|补肾强骨方对原发性骨质疏松症患者血清TRACP5b表达的影响

补肾强骨方对原发性骨质疏松症患者血清TRACP5b表达的影响

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目的 探讨补肾强骨方对原发性骨质疏松症患者血清TRACP5b表达的影响.方法 选取2017年1月~2017年7月丽水市中医院收治的60例原发骨质疏松患者,按照采用随机数字表法分为治疗组与对照组,治疗组口服钙尔奇D片+补肾强骨方治疗,对照组口服钙尔奇D片+福善美片,疗程3个月.观察比较2组患者的中医症状评分,骨密度,疼痛评分,骨折风险量表评估和实验室检查指标.结果 ①治疗3个月,治疗组较对照组症状明显改善(P<0.05);②随访3个月,治疗组骨密度测定较对照组显著改善(P<0.05);③治疗2个月、3个月后,治疗组疼痛评分、骨折风险评估、血清TRACP5b较对照组均显著改善(P<0.05).结论 补肾强骨方能有效缓解原发性骨质疏松症患者的临床症状,降低骨质疏松性骨折的风险.
Effect of Bushen Qianggu Fang on serum TRACP5b expression in patients with primary osteoporosis
Objective To investigate the effect of Bushen Qianggu Fang on serum TRACP5b expression in patients with primary osteoporosis. Methods A total of 60 patients with primary osteoporosis were selected from January 2015 to July 2017. The patients were divided into two groups: the treatment group and the control group. The treatment group was treated with oral Calcium D tablet + Bushen Qianggu fang treatment. The control group was treated with oral Erqi D film and Fu Shanmei tablet for 3 months. TCM symptom score, bone mineral density, pain score, fracture risk assessment, TRACP5b. Results ①After 3 months of treatment, the symptoms in the treatment group were significantly improved compared with the control group (P<0.05). ② Followed up for 6 months,the bone mineral density of the treatment group was significantly improved compared with the control group (P<0.05). After 2 months and 3 months, the pain score and the risk assessment of the treatment group and the serum TRACP5b in the treatment group were significantly improved compared with the control group (P<0.05) .Conclusion Bushen Qiangguang Fang can effectively relieve the clinical symptoms of patients, Inhibit excessive bone turnover, so that bone metabolism to achieve a new balance, improve bone mass.

Bushen Qianggu fangprimary osteoporosistartrate-resistant acid phosphatase 5 b

刘磊、周健

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丽水市中医院 骨伤科,浙江 丽水 323000

补肾强骨方 原发性骨质疏松症 抗酒石酸酸性磷酸酶5b

2016年丽水市科技计划项目

2016GYX47

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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