Clinical evaluation of tranexamic acid in patients with acute nonvariceal upper gastrointestinal bleeding
Objective To study the analysis of tranexamic acid in patients with acute non variceal upper gastrointestinal bleeding in clinical evaluation. Methods 86 patients with acute non variceal upper gastrointestinal bleeding in Jinhua Grace Hospital were selected as the subjects. The control group was given intravenous esomeprazole. The experimental group was given intravenous drip of tranexamic acid. The clinical efficacy, blood transfusion and related complications of the experimental group and the control group were compared and analyzed. Results After the corresponding treatment, the effective rate was 86.04% in the experimental group and 83.72% in the control group. The difference between the two groups was not statistically significant. The blood transfusion volume of the patients in the experimental group and the control group was (402.12±134.20)mL and (403.33±135.44)mL, respectively, and there was no statistical significance. In the experimental group, the incidence of angina pectoris and transient ischemic attack was 11.63%, significantly higher than that of the control group (0%), with statistical difference (P<0.05). Conclusion Tranexamic acid in patients with acute nonvariceal upper gastrointestinal hemorrhage in is not ideal, and may increase the angina pectoris and transient ischemic complications such as probability.