Safety and effectiveness of levofloxacin in the treatment of lower respiratory tract bacterial infection in AECOPD
Objective To investigate the clinical efficacy and safety of levofloxacin in the treatment of AECOPD lower respiratory tract bacterial infection. Methods A total of 78 patients with AECOPD lower respiratory tract bacterial infection admitted in Taizhou Hospital of Zhejiang Province from July 2016 to April 2017 were randomly divided into control group and study group, 39 cases each group.The study group were treated with levofloxacin, the control group were treated with ceftriaxone sodium. The effect, safety and costs in the two groups were compared. Results The total effective rate was 87.18% in the study group, 89.74% in the control group, the difference had no statistically significant. Nausea and vomiting, dizziness, rash and other adverse drug reaction rate in the two groups had no significant difference. tThe costs associated with levofloxacin in the study group was significantly less than the cost of ceftriaxone sodium in the control group, the difference had statistically significant(P<0.05). Conclusion The use of levofloxacin in the treatment of AECOPD lower respiratory tract bacterial infection has better clinical efficacy, safety and economy, and is beneficial to protect the quality of life and life safety of patients.
NETL
NSTL
万方数据
维普
