首页|康莱特注射液联合调强放疗治疗老年非小细胞肺癌的效果评价

康莱特注射液联合调强放疗治疗老年非小细胞肺癌的效果评价

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目的 探讨康莱特注射液联合调强放疗治疗老年非小细胞肺癌的临床效果.方法 选取杭州市萧山区第一人民医院2014年3月~2016年3月收治的68例老年非小细胞肺癌患者,双盲法随机分成2组,对照组(n=34)采用调强放疗,观察组(n=34)基于对照组加用康莱特注射液,比较2组近期疗效、生活质量改善情况及不良反应情况.结果 观察组RR率为76.5%,对照组RR率为70.6%,比较差异无统计学意义.2组治疗前SF-36评分比较无统计学意义,治疗后观察组SF-36评分为(594.2±62.8)分,明显高于对照组,且2组治疗后SF-36评分均明显高于本组治疗前(P<0.05).观察组WBC、中性粒细胞均高于对照组(P<0.05).结论 康莱特注射液联合调强放疗治疗老年非小细胞肺癌患者临床效果优良.
Evaluation of the efficacy of Kanglaite combined with intensity modulated radiotherapy in elderly patients with non-small cell lung cancer
Objective To investigate the clinical effect of Kanglaite combined with intensity modulated radiotherapy in the treatment of elderly non-small cell lung cancer. Methods 68 patients with non-small cell lung cancer (NSCLC) from March 2014 to March 2016 were randomly divided into two groups. The control group (n=34) was treated with intensity-modulated radiotherapy. The observation group (n=34) based on the control group plus Kanglaite, compared the two groups of recent efficacy, quality of life improvement and adverse reactions. Results There was no significant difference of RR between the two groups. There was no significant difference of SF-36 between the two groups before treatment, SF-36 of observation group was significantly higher than those of the control group (P<0.05). The SF-36 of two groups after treatment were significantly higher than those before treatment (P<0.05). The levels of WBC, neutrophils in the observation group were higher than those in the control group (P<0.05) . Conclusion Kanglaite combined with intensity modulated radiotherapy for elderly patients with non-small cell lung cancer clinical results are excellent, worthy of promotion.

elderly non-small cell lung cancerKanglaiteintensity modulated radiotherapy

徐小平、郭庆敏、姜贻乾、安素红、苏芳

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杭州市萧山区第一人民医院 放疗科,浙江 杭州 311200

老年非小细胞肺癌 康莱特注射液 调强放疗

杭州市科技计划项目

20130733Q45

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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