首页|硫酸镁与沙丁胺醇联合雾化吸入治疗重度支气管哮喘急性发作患者的疗效

硫酸镁与沙丁胺醇联合雾化吸入治疗重度支气管哮喘急性发作患者的疗效

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目的 探讨硫酸镁联合沙丁胺醇雾化吸入治疗重度支气管哮喘急性发作的临床效果.方法 选取金华市人民医院2016年1月~2017年7月收治的178例重度支气管哮喘急性发作患者,随机分为2组,各89例.对照组仅给予沙丁胺醇雾化治疗,观察组采取硫酸镁联合沙丁胺醇雾化吸入治疗.比较2组给药后肺功能上升率及临床疗效.结果 观察组给药后10、20 min时FEV1上升率和PEF上升率均显著高于对照组同期(P<0.01).治疗7 d后,观察组总有效率为91.01%,显著高于对照组的75.28%(P<0.01).结论 硫酸镁联合沙丁胺醇雾化吸入治疗重度支气管哮喘急性发作疗效显著,可迅速改善患者肺功能.
Effect of magnesium sulfate combined with salbutamol atomization on severe acute bronchial asthma
Objective To explore clinical effect of magnesium sulfate combined with salbutamol atomization on severe acute bronchial asthma. Methods 178 cases with severe acute bronchial asthma in our hospital from January 2016 to July 2017 were divided them into two groups, 89 cases in each group. Provided magnesium sulfate combined with salbutamol inhalation to observation group and provided salbutamol atomization to control group. Compared the increasing rate of pulmonary function after administration and clinical efficacy between two groups. Results The increase rate of FEV1 and the increase rate of PEF in the observation group after administration of 10 min, 20 min were significant higher than those in the control group at same time (P<0.01). After 7 d treatment, observation group's overall effective rate was 91.01%, which was significant higher than control group's 75.28% (P<0.01). Conclusion Magnesium sulfate combined with salbutamol atomization helps patients with severe acute bronchial asthma to improve pulmonary function with good clinical effect quickly.

magnesium sulfatesalbutamolaerosolized inhalationbronchial asthmasevere acute

傅顺金

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金华市人民医院 急诊科,浙江 金华 321000

硫酸镁 沙丁胺醇 雾化吸入 重度支气管哮喘 急性发作

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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