Effect of recombinant human erythropoietin β injection combined with maintain control nursing model on hemodialysis indexes and quality of life in patients with diabetic nephropathy
Objective To study the effect of recombinant human erythropoietin β injection combined with maintain control nursing model on hemodialysis indexes and quality of life in patients with diabetic nephropathy. Methods 76 patients of diabetic nephropathy who received therapy from April 2013 to June 2015 were selected as research objects. According to random number table, those patients were divided into the observation group (n=38) and the control group (n=38). Their were treated with hemodialysis, the control group was given maintenance control nursing mode, while the observation group was combined with recombinant human erythropoietin β injection, after one month of continuous treatment, the changes of renal function, hemodialysis index and quality of life were compared between the two groups before and after treatment. Results After treatment, the urinary protein excretion rate (UAER) and serum creatinine (SCr) of the two groups were significantly lower than those before treatment (P<0.05), the UAER and SCr in the observation group were significantly lower than those in the control group, the difference was statistically significant(P<0.05). After treatment, the urea clearance index of the two groups decreased significantly, and the hematocrit increased significantly (P<0.05), the urea clearance index in the observation group was significantly lower than those in the control group, and the hematocrit was higher than those in the control group, the difference was statistically significant(P<0.05) . After treatment, the quality of life scale scores in all dimensions of the two groups were significantly higher than those before treatment(P<0.05), the role function, physical function, emotional function, social function score and total score of the observation group were significantly higher than those in the control group, the difference was statistically significant(P<0.05). Conclusion Recombinant human erythropoietin β injection combined with maintain control nursing model is well for diabetic nephropathv, it is helpful to improve the renal function, hemodialysis indexes and the quality of life.
diabetic nephropathymaintain control nursing modelrecombinant human erythropoietin β injectionhemodialysis indexquality of life
NETL
NSTL
万方数据
维普
