首页|加味四物汤治疗寒凝血瘀型原发性痛经的疗效观察

加味四物汤治疗寒凝血瘀型原发性痛经的疗效观察

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目的 分析加味四物汤对寒凝血瘀型原发性痛经的临床治疗效果.方法 通过单盲、随机以及阳性药平行对照的分析手段进行研究,将2014年7月至2016年6月于海宁市第二人民医院接受诊治的寒凝血瘀型原发性痛经患者160例,分为治疗组和对照组各80例.治疗组给予加味四物汤治疗,对照组给予复方炔诺酮片或布洛芬胶囊治疗,疗程均为3个月经周期,观察痛经积分变化和临床疗效进行统计分析,并对加味四物汤临床应用的安全性进行评价.结果 治疗组痛经积分(5.4±2.2)显著低于对照组(10.9±3.0),差异具有统计学意义(P<0.05);治疗组总有效率(87.5%)显著高于对照组(75.0%),差异具有统计学意义(P<0.05);2组患者治疗期间未发生不良事件,一般体检指标未见异常.结论 加味四物汤治疗寒凝血瘀型原发性痛经疗效显著且临床应用安全性良好.
Clinical efficacy of Jiawei Siwu Tang on primary dysmenorrhea with cold accumulation and blood stasis
Objective To observe and analyze the clinical curative effect of Jiawei Siwu Tang on primary dysmenorrhea of cold coagulation and blood stasis type. Methods A total of 160 patients with primary dysmenorrhea were treated with single-blind, randomized, and positive drugs in the Second People's Hospital of Haining City from July 2014 to June 2016, and were randomly divided into treatment group and control group, 80 cases. The treatment group was treated with Jiawei Siwu Tang. The control group was treated with compound norethisterone tablets or ibuprofen capsules. The course of treatment was three menstrual cycles. The changes of symptoms and signs were observed and the clinical efficacy was analyzed statistically. Soup clinical application of the safety evaluation. Results The pain score (5.4±2.2) in the treatment group was lower than that in the control group (10.9±3.0), the difference was statistically significant (P<0.05). The total effective rate (87.5%) in the treatment group was significantly higher than that in the control group (75.0%), the difference was statistically significant (P<0.05). Two groups of patients during treatment did not occur adverse events, general physical examination indicators no abnormalities. Conclusion Jiawei Siwu Tang is effective in the treatment of primary dysmenorrhea with cold coagulation and blood stasis type and the clinical application is safe.

Jiawei Siwu Tangcold coagulation and blood stasis typeprimary dysmenorrhea

沈江平、朱庭舫

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海宁市第二人民医院 妇科,浙江 海宁 314400

加味四物汤 寒凝血瘀型 原发性痛经 疗效

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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