首页|琥珀酸亚铁治疗妊娠合并缺铁性贫血的疗效与安全性观察

琥珀酸亚铁治疗妊娠合并缺铁性贫血的疗效与安全性观察

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目的 分析琥珀酸亚铁治疗妊娠合并缺铁性贫血的疗效与安全性观察.方法 选取德清县人民医院收治的100例妊娠合并缺铁性贫血妇女为研究对象.对照组应用硫酸亚铁片进行治疗,试验组给予琥珀酸亚铁治疗.比较分析试验组与对照组RBC、HB水平、临床疗效和不良反应发生情况等临床指标.结果 试验组治疗有效率为90.0%,显著高于对照组有效率74.0%,差异具有统计学意义(P<0.05).治疗后,试验组患者Hb为(114.90±13.44)g/L,RBC为(3.87±0.82)×1012/L,对照组Hb为(102.91±10.52)g/L,RBC为(3.32±0.66)×1012/L,2组差异具有统计学意义(P<0.05).试验组不良反应发生率为6.0%,显著低于对照组的发生率22.0%,差异具有统计学意义(P<0.05).结论 琥珀酸亚铁治疗妊娠合并缺铁性贫血的临床疗效较为理想,安全性较高,不良反应轻微.
Observation on the efficacy and safety of ferrous succinateon the treatment of iron deficiency anemia in pregnancy
Objective To investigate the efficacy and safety of ferrous succinate on the treatment of iron deficiency anemia in pregnancy. Methods 100 pregnant women with iron deficiency anemia in Deqing county people's hospital were selected as the subjects. The control group was treated with ferrous sulfate tablets, and the experimental group was treated with ferrous succinate, 3 tablets a day. RBC, HB levels, clinical efficacy and adverse reactions and other clinical indicators in the two groups were compared. Results The effective rate in the experimental group was 90%, which was significantly higher than that in the control group 74%, the difference was statistically significant (P<0.05). After treatment, Hb was (114.90±13.44) g / L, RBC was (3.87±0.82)×1012/L in the experimental group, while in the control group Hb was (102.91±10.52) g/L, RBC was (3.32±0.66)×1012/L, the differences had statistically significant (P<0.05). The adverse reaction rate in the experimental group was 6%, which was significantly lower than that in the control group 22%, the difference was statistically significant (P<0.05). Conclusion Ferrous succinate efficacy in the treatment of pregnant women with iron deficiency anemia is ideal, high safety, mild adverse reactions.

ferrous succinatepregnancyiron deficiency anemia

全晓瑜、丁伟平

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德清县人民医院 妇产科,浙江 德清 313200

琥珀酸亚铁 妊娠 缺铁性贫血

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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