米非司酮配伍米索前列醇不同给药方式对早中期妊娠引产的效果对比
Comparison of the effects of the different administration methods of mifepristone and misoprostol on induction of labor in early and middle trimester pregnancy
方徐芬 1王辰玥1
作者信息
- 1. 杭州市中医院 妇产科,浙江 杭州 310000
- 折叠
摘要
目的 探讨米非司酮配伍米索前列醇不同给药方式对早中期妊娠引产的临床应用效果.方法 2组早中期妊娠产妇均接受米非司酮配伍米索前列醇引产,对照组经传统口服给药,研究组给予口服米非司酮联合阴道放置米索前列醇引产.记录并比较2组早中期妊娠产妇引产效果、不良反应(药物相关)发生率.结果 研究组早中期妊娠产妇引产有效率为91.30%,显著高于对照组的73.91%(P<0.05).研究组恶心、呕吐等药物相关不良反应发生率均显著低于对照组(P<0.05).结论 口服米非司酮、阴道放置米索前列醇可显著提高早中期妊娠引产有效性、安全性.
Abstract
Objective To investigate the clinical effect of the different administration methods of mifepristone and misoprostol on induction of labor in early and middle trimester pregnancy. Methods Two groups were treated with mifepristone and misoprostol, and the control group were given oral administration. The study group was given oral mifepristone combined with vaginal misoprostol to induce labor. The effect of induced labor and the incidence of adverse reactions (drug related) were recorded and compared in the two groups. Results The abortion rate in the study group (91.30%) was significantly higher than 73.91% in the control group (P<0.05). The adverse reactions such as nausea and vomiting drugs in study group were significantly lower than those in the control group (P<0.05). Conclusion The application of mifepristone and vaginal misoprostol can significantly improve the effectiveness and safety of early and mid-term pregnancy induced labor.
关键词
妊娠引产/米非司酮/米索前列醇Key words
trimester pregnancy induced labor/mifepristone/misoprostol引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据