Clinical observation of intravenous infusion of Magnesium Sulfate and oral Nifedipine Controlled Release Tablets in the treatment of pregnancy induced hypertension
Objective To study the clinical efficacy of oral Nifedipine Controlled Release Tablets combined with intravenous drip of Magnesium Sulfate in the treatment of pregnancy induced hypertension. Methods 100 cases of pregnancy induced hypertension from June 2015 to August 2017 in our hospital were selected as the subjects, were randomly divided into control group and experimental group, 50 cases in each group. The control group was treated with Magnesium Sulfate, intravenous drip, once a day. The experimental group was given Nifedipine Controlled Release Tablets orally, three times a day, 10 mg times. The diastolic blood pressure, systolic blood pressure and clinical curative effect were compared between the experimental group and the control group before and after treatment. Results After treatment, the effective rate was 94.0%in the experimental group and 84.0% in the control group, and the difference was statistically significant (P<0.05). Before treatment, there was no significant difference between the experimental group and the control group in diastolic blood pressure and systolic blood pressure. After treatment, the systolic blood pressure and systolic blood pressure in the experimental group were (130.21 ± 6.32) mmHg, and (80.04 ±5.22) mmHg, significantly lower than that of the control group, with statistical difference (P<0.05). Conclusion Oral and intravenous drip of Nifedipine Controlled Release Tablets Magnesium Sulfate clinical effect in the treatment of hypertension in pregnancy is more ideal, can significantly improve the blood pressure condition, high safety, has clinical significance.