首页|黄体酮软胶囊用于早期先兆流产保胎治疗的效果观察

黄体酮软胶囊用于早期先兆流产保胎治疗的效果观察

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目的 研究早期先兆流产保胎中应用黄体酮软胶囊临床效果.方法 选取温州市龙湾区第一人民医院门诊治疗的100例早期先兆流产患者为研究对象.对照组给予黄体酮注射液,每次为20 mg,1次/d.试验组给予黄体酮软胶囊,口服,每次剂量为100 mg.比较分析试验组与对照组患者的不良反应发生情况、血清孕酮水平及保胎成功率等临床指标.结果 试验组血清孕酮值为(48.12±3.23)μg/L显著高于对照组血清孕酮水平(36.50±5.12)μg/L,差异具有统计学意义(P<0.05).试验组不良反应发生率为8.0%,对照组不良反应发生率为24.0%,差异具有统计学意义(P<0.05).试验组保胎成功率为94.0%,显著高于对照组的84.0%,差异具有统计学意义(P<0.05).结论 早期先兆流产保胎中应用黄体酮软胶囊临床效果较为理想,安全性高,发生不良反应轻微,保胎成功率高,服用方便.
Observation on the tocolytic effect of progesterone soft capsules on the treatment of the women with early threatened abortion
Objective To study the tocolytic effect of progesterone soft capsules on the treatment of the women with early threatened abortion. Methods 100 cases with early threatened abortion in the first people's hospital, Longwan district were selected as the object of this study. The control group were given progesterone injection, once for 20 mg, 1 times/d. The experimental group were given progesterone capsule orally, and the dose was 100 mg. The adverse reaction, serum progesterone and the success rate of tocolytic in the two groups were compared. Results The serum progesterone in the experimental group was (48.12±3.23) μg/L, which was significantly higher than that in the control group (36.50±5.12) μg/L, the difference was statistically significant (P<0.05). The adverse reaction rate in the experimental group was 8.0%, and in the control group was 24%, the difference was statistically significant (P<0.05). The success rate of tocolytic was 94.0% in the experimental group, which was significantly higher than that in the control group 84.0%, the difference was statistical significant (P<0.05). Conclusion Progesterone soft capsules applied for early threatened abortion, the clinical effect is ideal, high safety, less adverse reaction, high success rate, convenient use.

progesterone soft capsulesearly threatened abortion

陈婷婷、王彩霞、王茜

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温州市龙湾区第一人民医院 妇产科,浙江 温州 325024

黄体酮软胶囊 早期先兆流产 保胎效果

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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