Effect of pathogenic microbiological detection combined with drug sensitivity test on rational use of antibiotics in children with bacterial diarrhea
Objective To investigate the effect of pathogenic microbiological detection combined with drug susceptibility test on the rational use of antibiotics in children with bacterial diarrhea. Methods From October 2015 to June 2017, 147 cases of children with bacterial diarrhea in our hospital were selected as the study object, the stool samples were collected after admission, then pathogenic microbiological testing and drug susceptibility testing was conduct to analyze pathogenic microbial distribution and its resistance to antibiotics. Results 132 strains of pathogenic microorganisms were detected from all the 147 cases of bacterial diarrhea in children, the composition ratio of Shigella was 46.21% (61/132), Escherichia coli accounting for 22.73% (30/132), Vibrio accounted for 15.91% (21/132), aeromonas aeruginosa accounted for 8.33% (11/132), other strains accounted for 6.82% (9/132). All kinds of pathogenic microorganisms were resistant to different antibiotics. Vibrio and Aeromonas hydrophila were resistant to ampicillin, which were 90.48% (19/21), 81.82% (9/11), respectively. Conclusion Pathogenic microbial detection and drug sensitivity test in children with bacterial diarrhea can accurately grasp the distribution of pathogenic microorganisms and antibiotic resistance to commonly used antibiotics, it is conducive to guiding the rational use of antibiotics.
bacterial diarrheapathogenic microorganismsdrug susceptibility testantibioticsrational use