Clinical effect of tiotropium combined with Seretide in the treatment of patients with chronic obstructive pulmonary diseases
Objective To study the clinical efficacy of tiotropium combined with Seretide in the treatment of patients with chronic obstructive pulmonary diseases. Methods 80 cases of patients with stable chronic obstructive pulmonary disease patients treated in our hospital from June 2015 to May 2017 as the research object, they were randomly divided into two groups, with 40 cases in each group. The control group was treated with tiotropium bromide, the experimental group was treated with tiotropium combined with Seretide. The arterial carbon dioxide partial pressure, oxygen partial pressure, FEV1 and FEV1,/FVC were compared between the experimental group and the control group before and after treatment. Results After the corresponding treatment, FEV1 in the experimental group was (2.27±0.45) L, significantly higher than that of the control group (1.80± 0.20) L (P<0.05). The FEV1 /FVC in the experimental group was (68.90±5.22), in the control group was (54.33±4.20), the difference between the two groups was statistically significant (P<0.05). After treatment, the oxygen partial pressure in the experimental group was(75.09±6.33) mmHg, which was significantly higher than that in the control group (66.33±4.76) mmHg (P<0.05). The arterial carbon dioxide in the experimental group was (44.30±2.67) mmHg, which was significantly lower than that in the control group(P<0.05). Conclusion The clinical effect of tiotropium combined with Seretide in the treatment of patients with chronic obstructive pulmonary disease is ideal, can significantly improve the pulmonary function of patients, relieve the clinical symptoms.