Meta analysis of curative effect of gefitinib in the treatment of non-small cell lung cancer
Objective To evaluate the safety and efficacy of targeted therapy for non - small cell lung cancer (NSCLC). Methods Computer retrieval data network at home and abroad, retrieval time limit from 2009 to 2013, collected the curative effect of different treatments on non-small cell lung cancer. According to include and exclude standard, after screening of literature and data analysis, extract data using Rev Man 5.0 software for Meta analysis. Results A total of ten randomized controlled trials were included in this analysis, with a total of 806 cases of patients. Meta analysis results show that compared with traditional chemotherapy complete response rate of the disease (CR = 1.93, 95% CI: 1.23-1.23, P = 0.004), disease objective efficient (RR = 1.72, 95% CI: 1.24-1.24, P = 0.001). The above data are statistically significant. Side effects in a stable condition, all the problems in the controllable range. Conclusion Targeted therapy can significantly reduce the risk of nausea and vomiting and kidney damage, but there is no significant side effects such as diarrhea, rashes.
NETL
NSTL
万方数据
维普
