Effect of budesonide fomoterol on CCL28 in asthma patients
Objective To investigate the effect of budesonide fomoterol on CCL28 expression in the serum of asthma patients. Methods Asthma patients in acute exacerbation were taken the venous blood. After the separation of serum, the content of CCL28 were tested. The patients received budesonide fomoterol treatment. All the patients received CCL28 detection one week later. Results The CCL28 level in patients of acute exacerbation was (37.58±3.64) ng/mL. After budesonide fomoterol treatment, the CCL28 level in patients was (10.37±1.05) ng/mL. Conclusion Budesonide fomoterol could significantly reduce CCL28 level of asthma patients in acute exacerbation, and may play an important role in inhibiting the eosinophilic inflammation in acute asthma.