Clinical observation on the effect of compound dihydroartemisinin on the treatment of the patients with imported malaria
Objective To study the effect of compound dihydroartemisinin on the treatment of the patients with imported malaria. Methods A randomized selection of 124 cases with imported malaria from January 2012 to January 2016 was included in the study. The control group were treated with compound naphthyl phosphate quinoline. The observation group were treated with compound dihydroartemisinin tablets. The clinical effect in the two groups was evaluated. The mean time of fever and the duration of the parasite were recorded. The adverse reactions were observed and recorded. Results The clinical cure rate and recovery rate were 98.39% (61/62) and 1.61% (1/62) in the observation group, and 96.77% (60/62) and 2.23% (2/62) in the control group, the difference in the two groups were no statistically significant. The mean antipyretic time and parasite clearance time were (26.2±9.2) h, (47.9±18.8) h respectively in the observation group, and (27.3±8.8) h, (48.6±19.3) h respectively in the control group the difference in the two groups were no statistically significant. The adverse reaction rate was 2.23% (2/62) in the observation group, which was significantly lower than that in the control group (16.13%, 10/62, χ2=35.71, P=0.00). Conclusion Compound dihydroartemisinin tablets and compound naphthoquine phosphate tablets can achieve good results in the treatment of imported malaria, but the former has less adverse reactions, so the patients are easy to tolerate and deserve to be treated as the preferred treatment for imported malaria patients.
NETL
NSTL
万方数据
维普
