首页|硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的效果分析

硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的效果分析

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目的 讨论硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的效果分析.方法 选取2014年6月~2016年6月杭州市第一人民医院治疗的老年2型糖尿病肾病合并高血压的患者60例,根据实行治疗方法不同分为对照组和实验组,每组各30例.其中对照组中使用硝苯地平控释片治疗,在实验组中使用硝苯地平控释片联合缬沙坦治疗.结果 治疗后的收缩压、舒张压、尿素氮、24小时的尿微量清蛋白排泄率小于治疗前,差异具有统计学意义(P<0.05).实验组的收缩压、舒张压、24小时的尿微量清蛋白排泄率小于对照组,差异具有统计学意义(P<0.05).实验组的不良反应小于对照组,差异具有统计学意义(P<0.05).结论 对老年2型糖尿病肾病合并高血压的患者实行硝苯地平控释片联合缬沙坦治疗,能够减少并发症的发生,具有重要的临床价值.
Effect of Nifedipine Controlled Release tablets combined with valsartan on elderly patients with type 2 diabetic nephropathy complicated with hypertension
Objective To evaluate the efficacy of Nifedipine Controlled Release tablets combined with valsartan in the treatment of elderly patients with type 2 diabetic nephropathy with hypertension. Methods Selected 60 cases type 2 diabetic nephropathy with hypertension patients from June 2014 to June 2016 treated by Hangzhou First People's Hospital, according to different treatment methods were divided into two groups,control group and experimental group,30 cases in each group.The control group used in the treatment of the use of Nifedipine Controlled Release Tablets, and the experimental group were treated with Nifedipine Controlled Release Tablets combined with valsartan. Results After treatment, systolic blood pressure, diastolic blood pressure, urea nitrogen and urinary albumin excretion rate of 24 hours were smaller than those before treatment, and the difference was statistically significant (P<0.05). The systolic blood pressure, diastolic blood pressure and urinary albumin excretion rate of the experimental group were less than those of the control group in 24 hours, the difference was statistically significant (P<0.05). The adverse reactions in the experimental group were smaller than those in the control group, and the difference was statistically significant (P<0.05). Conclusion The treatment of Nifedipine Controlled Release tablets combined with valsartan in elderly patients with type 2 diabetic nephropathy with hypertension can reduce the incidence of complications, and has important clinical value.

Nifedipine Controlled Released tabletsvalsartansenile type 2 diabetic nephropathyhypertension

王江涛

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杭州市第一人民医院 药剂科,浙江 杭州 310006

硝苯地平控释片 缬沙坦 老年2型糖尿病肾病 高血压

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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