中国生化药物杂志2017,Vol.37Issue(11) :157-158.DOI:10.3969/j.issn.1005-1678.2017.11.067

纳洛酮联合早期神经康复介入治疗急性酒精中毒致偏瘫的临床疗效观察

Clinical observation of naloxone combined with early rehabilitation intervention in the treatment of acute alcoholism induced hemiplegia

罗定 周羽
中国生化药物杂志2017,Vol.37Issue(11) :157-158.DOI:10.3969/j.issn.1005-1678.2017.11.067

纳洛酮联合早期神经康复介入治疗急性酒精中毒致偏瘫的临床疗效观察

Clinical observation of naloxone combined with early rehabilitation intervention in the treatment of acute alcoholism induced hemiplegia

罗定 1周羽2
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作者信息

  • 1. 浙江省宁波市鄞州人民医院,浙江 宁波 315040
  • 2. 浙江省宁波市鄞州第二医院,浙江 宁波 315040
  • 折叠

摘要

目的 探讨纳洛酮联合早期神经康复介入治疗急性酒精中毒致偏瘫的临床疗效.方法 于2014年1月~2017年5月期间,选取浙江省宁波市鄞州人民医院收治的60例急性酒精中毒致偏瘫患者随机分为2组,每组30例,对照组采取纳洛酮治疗,观察组采取纳洛酮联合早期神经康复介入治疗,比较2组临床疗效、神经功能缺损评分、日常生活能力评分、肢体功能评分.结果 观察组的总有效率为93.33%,明显高于对照组的73.33%(P<0.05).治疗后,观察组的神经功能缺损评分高于对照组(P<0.05),其日常生活能力评分、肢体功能评分均低于对照组(P<0.05);观察组的生活质量评分明显高于对照组(P<0.05).结论 在急性酒精中毒致偏瘫患者中,采用纳洛酮联合早期神经康复介入治疗具有显著的临床疗效,可有效改善神经功能、肢体功能、日常生活能力.

Abstract

Objective To discuss the clinical efficacy of naloxone combined with early rehabilitation intervention in the treatment of acute alcoholism induced hemiplegia. Methods 60 cases of patients with acute alcohol poisoning induced hemiplegia in Yinzhou people's hospital of Ningbo from January 2014 to May 2017 were selected and randomly divided into two groups, 30 cases in each group, the control group took naloxone treatment, the observation group took naloxone combined with early rehabilitation intervention, the clinical efficacy, neurological deficit score, ADL score and limb function score were compared between two groups. Results The total effective rate in the observation group was 93.33%, was significantly higher than the control group 73.33% (P<0.05). After treatment, the neurological function score in the observation group was higher than the control group (P<0.05), the ADL score and limb function score were lower than the control group (P<0.05). Conclusion In the acute alcohol poisoning patients with hemiplegia, using naloxone combined with early rehabilitation intervention has significant clinical efficacy, can effectively improve the nerve function, limb function and daily living ability.

关键词

急性酒精中毒/偏瘫/纳洛酮/神经康复介入治疗

Key words

acute alcoholism/hemiplegia/naloxone/neurological rehabilitation interventional therapy

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
参考文献量9
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