首页|槐杞黄颗粒辅治难治性支原体肺炎患儿的效果及对其免疫、炎症指标的影响

槐杞黄颗粒辅治难治性支原体肺炎患儿的效果及对其免疫、炎症指标的影响

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目的 探讨槐杞黄颗粒辅助治疗难治性支原体肺炎患儿的临床疗效,并分析对免疫、炎症指标的影响.方法 选取2014年2月~2017年3月山东大学第二医院收治的80例诊断为难治性小儿肺炎患者为研究对象,参照随机数字表分为对照组与观察组,每组各40例.对照组予以抗感染、营养支持等对症治疗,观察组加用槐杞黄颗粒.观察2组治疗效果,比较2组免疫功能及炎性因子,并统计不良反应、复发情况.结果 治疗后,观察组总有效率为95.0%,显著高于对照组的80.0%(P<0.05);治疗后,观察组IgA、CD4均显著高于对照组,IL-6、TNF-α显著低于对照组(P<0.05);2组均无不良反应发生.结果槐杞黄颗粒用于辅助治疗难治性支原体肺炎患儿临床疗效较好,显著促进恢复健康,临床可予以考虑.
Effects of Huaiqihuang granules on the children with refractory mycoplasma pneumonia and the influence on immune and inflammatory indexes
Objective To explore the effects of Huaiqihuang granules on children with refractory mycoplasma pneumonia and the influence on immune and inflammatory indexes. Methods 80 cases of children diagnosed with refractory pneumonia were selected and randomly divided into the control group (n=40) and the observation group (n=40). The control group was given anti-infection and nutritional support, and the observation group was additionally given Huaiqihuang granules. The efficacy was observed, and the immune function and inflammatory factors were compared, and the adverse reactions and recurrence situations were recorded. Results After treatment, the total effective rate in the observation group was significantly higher than that in the control group (95.0% vs 80.0%) (P<0.05). The levels of IgA and CD4 in the observation group were significantly higher while the levels of IL-6 and TNF-α were significantly lower than those in the control group (P<0.05). There was no adverse reaction in the two groups. Conclusion The clinical efficacy of Huai Qi Huang granules in the adjuvant treatment of refractory Mycoplasma pneumonia is better, and significantly promote the recovery of health, clinical consideration.

Huaiqihuang granulesrefractorypediatric pneumoniaimmune functioninflammatory indexes

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山东大学第二医院 药学部,山东 济南 250033

槐杞黄颗粒 难治性 小儿肺炎 免疫功能 炎性指标

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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