米非司酮治疗异位妊娠的效果及对患者生育力的影响
Effect of mifepristone on ectopic pregnancy and its influence on the fertility
宋紫凤 1张春玉1
作者信息
- 1. 宁波市明州医院 产科,浙江 宁波 315000
- 折叠
摘要
目的 探讨米非司酮治疗早期异位妊娠的有效性及对患者生育力的影响.方法 选取2011年1月~2012年12月宁波市明州医院收治的早期异位妊娠患者90例,采取不同方法治疗,对比2组患者治疗有效性以及生育力.结果 治疗前,2组患者的β-HCG(人绒毛膜促性腺激素)以及包块直径无明显区别,治疗后均得到一定改善,研究组显著优于对照组(P<0.05);研究组患者宫内妊娠率显著高于对照组(P<0.05),异位妊娠以及继发性不孕率显著低于对照组(P<0.05);研究组患者的治疗有效率高于对照组同时不良反应发生率低于对照组(P<0.05).结论 早期异位妊娠患者应米非司酮治疗的效果理想,有利于保留患者生育力.
Abstract
Objective To investigate the effect of mifepristone on the treatment of early ectopic pregnancy and influence on the fertility. Methods 90 cases with ectopic pregnancy from January 2011 to December 2012 in Mingzhou hospital, were given different treatment methods, effect and fertility were compared between the two groups. Results β-HCG(human chorionic gonadotropin) and mass diameter in the two groups before treatment had no significant difference, which were improved after treatment, the study group was significantly better than those in the control group (P<0.05); the intrauterine pregnancy rate in the study group was significantly higher than that in the control group (P<0.05), secondary infertility and ectopic pregnancy rate was significantly lower than that in the control group (P<0.05). The effective rate in the study group was higher than that in the control group and the incidence of adverse reaction was lower than that in control group (P<0.05). Conclusion The effect of mifepristone should be ideal for early ectopic pregnancy, which is beneficial to preserve the fertility of the patient.
关键词
米非司酮/甲喋呤/早期异位妊娠/生育力Key words
mifepristone/methotrexate/early ectopic pregnancy/fertility引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据