Effect of cetirizine on allergic rhinitis and the influence on inflammatory factors
Objective To investigate the clinical effect of cetirizine in patients with allergic rhinitis and the effect on inflammatory factors. Methods 150 patients with allergic rhinitis admitted in the first hospital in Jiaxing from January 2016 to February 2017 were randomly divided into two groups. The control group were treated with routine therapy. The study group were received routine therapy combined with cetirizine . The effects and changes in inflammatory factors were compared in the two groups. Results The clinical effect in the study group was significantly better than that in the control group (P<0.05). Before treatment, there was no significant difference in TNF-α and IL-4 between the two groups. After treatment, TNF-α and IL-4 in the study group were significantly lower than those in the control group (P<0.05). The VAS score in the study group was lower than that in the control group (P<0.05) .There was no significant difference in adverse reaction between the two groups. Conclusion The application of cetirizine in patients with allergic rhinitis is helpful to improve the clinical effect and reduce the level of inflammatory factors.
NETL
NSTL
万方数据
维普
