首页|银杏达莫注射液联合亚低温治疗对重型颅脑损伤患者手术效果的影响

银杏达莫注射液联合亚低温治疗对重型颅脑损伤患者手术效果的影响

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目的 分析银杏达莫注射液联合亚低温治疗对重型颅脑损伤患者手术效果的影响.方法 选取天津市咸水沽医院收治的46例重型颅脑损伤患者为研究对象.实验组与对照组均进行手术治疗,对照组给予改良去大骨瓣减压术,实验组进行银杏达莫注射液联合亚低温治疗,比较分析2组患者昏迷评分、MDA及血清清蛋白水平等临床指标.结果 经过对应治疗后,实验组GCS评分(12.89±1.78)显著高于对照组评分(10.20±1.33)分,差异具有统计学意义(P<0.05).实验组治疗后血清清蛋白水平(33.20±3.21)g/L,对照组血清清蛋白水平(31.21±2.65)g/L,差异具有统计学意义(P<0.05).对照组SOD水平(77.20±1.77)mU/L显著低于实验组SOD水平(82.30±1.33)mU/L,差异具有统计学意义(P<0.05).对照组中,12例患者预后良好,实验组中,16例患者预后良好,2组差异具有统计学意义(P<0.05).结论 银杏达莫注射液联合亚低温治疗对重型颅脑损伤患者手术效果较为理想,可显著提高预后效果,帮助患者恢复意识,改善相关临床指标.
Effect of Yinxing Damo Zhusheye combined with mild hypothermia on the operation of patients with severe craniocerebral injury
Objective To study and analyze the effect of Yinxing Damo Zhusheye combined with mild hypothermia treatment on severe craniocerebral injury patients. Methods 46 patients with severe craniocerebral injury in Tianjin Xianshuigu Hospital were selected as the object of study. The experimental group and the control group were treated with surgery, the control group was given modified decompressive craniectomy, the experimental group was given ginkgo leaf extract and dipyridamole injection combined with hypothermia, coma score, clinical index MDA and serum albumin level in two groups of patients were compared and analyzed. Results After the treatment, GCS score of the experimental group was (12.89±1.78) was significantly higher than the control group score (10.20±1.33), with statistical difference (P<0.05). The experimental group after treatment, serum albumin level (33.20±3.21) g/L, the control group of serum albumin level (31.21±2.65) g/L, with statistical difference (P<0.05). The level of SOD in the control group was (77.20±1.77) mU/L, which was significantly lower than that of the experimental group, and the level of SOD was (82.30±1.33) mU/L, with statistical difference (P<0.05). In the control group, the prognosis of 12 patients was good. In the experimental group, the prognosis of 16 patients was good, and the difference between the two groups was statistically significant (P<0.05). Conclusion Yinxing Damo Zhusheye therapy combined with mild hypothermia in patients with severe head injury surgery, could significantly improve the prognosis, help patients regain consciousness, and improve the relevant clinical indexes.

Yinxing Damo Zhusheyemild hypothermia treatmentsevere traumatic brain injuryoperation effect

韩永成、张宏远

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天津市咸水沽医院 脑系科,天津 300350

银杏达莫注射液 亚低温治疗 重型颅脑损伤 手术效果

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
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