中国生化药物杂志2017,Vol.37Issue(11) :190-192.DOI:10.3969/j.issn.1005-1678.2017.11.082

蒲地蓝联合抗感颗粒对流行性腮腺炎患儿住院时间、退热时间及腮腺消肿时间的影响

Influence of hospitalization time, fever time and swelling time of parotid gland in Pu Dilan combined with anti-sense particles in children with mumps

郑晓清 李昌崇
中国生化药物杂志2017,Vol.37Issue(11) :190-192.DOI:10.3969/j.issn.1005-1678.2017.11.082

蒲地蓝联合抗感颗粒对流行性腮腺炎患儿住院时间、退热时间及腮腺消肿时间的影响

Influence of hospitalization time, fever time and swelling time of parotid gland in Pu Dilan combined with anti-sense particles in children with mumps

郑晓清 1李昌崇2
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作者信息

  • 1. 温州医科大学 研究生院,浙江 温州 325000
  • 2. 温州医科大学附属第二医院 儿童呼吸科, 浙江 温州 325000
  • 折叠

摘要

目的 探讨蒲地蓝联合抗感颗粒对流行性腮腺炎患儿住院时间、退热时间及腮腺消肿时间的影响.方法 随机选取2013年1月~2016年12月温州医科大学附属第二医院儿科收治的流行性腮腺炎住院患儿100例,随机分为观察组(n=50)和对照组(n=50),对照组的患儿给予常规治疗,包括退热、支持疗法及其他对症治疗,观察组在对照组常规治疗的基础上加用蒲地蓝口服液联合抗感颗粒,观察并比较2组患儿的住院时间、退热时间、腮腺消肿时间、临床疗效及其并发症发生等情况.结果 与对照组比较,观察组患儿的总有效率明显升高(86.00%vs.60.00%),差异具有统计学意义(P<0.01);与对照组比较,观察组患儿的退热时间、腮腺消肿时间、住院时间均明显缩短,差异具有统计学意义(P<0.05);在并发症发生情况方面,2组不良发应发生率差异有统计学意义(P<0.05).结论 与传统的常规治疗相比,用蒲地蓝联合抗感颗粒治疗患有流行性腮腺炎小儿的疗效更好,治愈率更高,病程缩短,并发症发生率降低,且安全性较好.

Abstract

Objective To explore the influence of hospitalization time, fever time and swelling time of parotid gland in Pu Dilan combined with anti-sense particles in children with mumps. Methods 100 patients from January 2016 to December 2013 with mumps in our hospital were randomly divided into observation group (n = 50) and control group (n = 50).Children in the control group were given routine treatment, including fever, supportive therapy and other symptomatic treatment, the observation group children were based on the conventional treatment plus Pu Dilan oral solution combined with anti-sense particles. To observe and compare the hospitalization time, fever time, parotid swelling time, clinical curative effect and complication of the two groups. Results Compared with the control group, the total effective rate of the observation group was significantly higher (86.00% vs. 60.00%), the difference was statistically significant (P<0.01). Compared with the control group, the fever time, parotid swelling time and hospitalization time of the observation group were significantly shortened, the difference was statistically significant (P<0.05).In the incidence of complications, the incidence of adverse hair loss between the two groups was statistically significant (P<0.05). Conclusion Compared with the traditional conventional treatment, the use of Podi blue combined with anti-sense particles in the treatment of children with mumps better efficacy, higher cure rate, shorten the course of disease, reduce the incidence of complications, and better security.

关键词

蒲地蓝/抗感颗粒/流行性腮腺炎/小儿

Key words

Pu Dilan/resistant particles/mumps/children

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
参考文献量6
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