Effect of glucosamine combined with sodium hyaluronate on the treatment of knee osteoarthritis
Objective To analyze the clinical efficacy of glucosamine combined with sodium hyaluronate in the treatment of knee osteoarthritis. Methods 112 patients with knee osteoarthritis were divided into the basal group (n=56) and the study group(n=56). The basal group were treated with oral glucosamine hydrochloride alone. The study group were treated with glucose and sodium hyaluronate. The changes of pain score (VAS) and knee function (Lysholm) before and after treatment in both groups and the clinical effect were observed. Results After treatment, the total effective rate was 75.00% in the basal group and 94.64% in the study group, the difference between the two groups was statistically significant (P<0.05). The VAS score of the study group was lower than that of the baseline group, and the Lysholm score of the study group was significantly higher than that of the baseline group Lysholm score, the difference between the two groups was statistically significant (P<0.05). Conclusion Glucosamine combined with sodium hyaluronate is effective in the treatment of knee osteoarthritis, which can effectively relieve pain and improve joint function and high safety.