Myocardial protective effects of different cardioplegia infusion during coronary artery bypass grafting
Objective To investigate the myocardial protection of coronary artery bypass grafting under cardiopulmonary bypass (CPB). Methods 88 patients with coronary heart disease from February 2015 to April 2017 were selected and underwent off-pump coronary artery bypass surgery, patients were divided into cold crystalloid group (n=44) and blood group (n=44) according to patient choosing different cardioplegia perfusion cardioplegia perfusion. Cold crystalloid group were treated with cold crystalloid cardioplegia perfusion, blood group were treated with blood cardioplegia perfusion. CK-MB detection value before surgery, immediately after aorta opening, postoperative 6 hs, 12 hs, 1 day after surgery, postoperative 2 days in two groups were recorded and compared. Results CK-MB level after aortic opening to the immediate postoperative 12 h in two groups showed an upward trend, and after the postoperative 1 day decreased gradually (P<0.05), but there was no significant difference between the two groups at the same. Conclusion The myocardial protective effects of different cardioplegic solutions on coronary artery bypass grafting are similar, but cold crystalloid cardioplegia is more economics for patients.