体外循环冠状动脉搭桥术中采用不同停跳液灌注的心肌保护作用研究
Myocardial protective effects of different cardioplegia infusion during coronary artery bypass grafting
林霞 1应晓珍2
作者信息
- 1. 丽水市中心医院 胸外科,浙江 丽水 323000
- 2. 丽水市中心医院 放疗科,浙江 丽水 323000
- 折叠
摘要
目的 探讨体外循环下冠状动脉搭桥手术中不同停跳液灌注的心肌保护作用.方法 选取丽水市中心医院2015年2月~2017年4月收治的88例冠心病患者,均接受体外循环冠状动脉搭桥手术治疗,根据患者选择灌注的不停跳液不同均分为冷晶体组(n=44)和含血组(n=44).冷晶体组患者给予冷晶体不停跳液灌注,含血组患者给予含血不停跳液灌注,记录并比较2组患者手术前、主动脉开放后即刻、术后6 h、术后12 h、术后1 d、术后2 d的CK-MB检测值.结果 术中2组主动脉开放后即刻至术后12 h CK-MB水平均呈上升趋势,至术后1 d之后CK-MB水平则逐渐降低(P<0.05),但2组各时间段CK-MB检测结果对比差异无统计学意义.结论 不同停跳液对体外循环冠状动脉搭桥术患者心肌保护作用相近,但冷晶体停跳液性价比更高.
Abstract
Objective To investigate the myocardial protection of coronary artery bypass grafting under cardiopulmonary bypass (CPB). Methods 88 patients with coronary heart disease from February 2015 to April 2017 were selected and underwent off-pump coronary artery bypass surgery, patients were divided into cold crystalloid group (n=44) and blood group (n=44) according to patient choosing different cardioplegia perfusion cardioplegia perfusion. Cold crystalloid group were treated with cold crystalloid cardioplegia perfusion, blood group were treated with blood cardioplegia perfusion. CK-MB detection value before surgery, immediately after aorta opening, postoperative 6 hs, 12 hs, 1 day after surgery, postoperative 2 days in two groups were recorded and compared. Results CK-MB level after aortic opening to the immediate postoperative 12 h in two groups showed an upward trend, and after the postoperative 1 day decreased gradually (P<0.05), but there was no significant difference between the two groups at the same. Conclusion The myocardial protective effects of different cardioplegic solutions on coronary artery bypass grafting are similar, but cold crystalloid cardioplegia is more economics for patients.
关键词
体外循环冠状动脉搭桥术/停跳液/冷晶体/含血/心肌保护Key words
extracorporeal circulation coronary artery bypass grafting/cardioplegia/cold crystalloid/blood/myocardial preservation引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据