Effect of celecoxib combined with eperisone hydrochloride on the treatment of the quinquagenarian with hyperextension injury of cervical spine
Objective To explore effect of celecoxib combined with eperisone hydrochloride on the treatment of the quinquagenarian with hyperextension injury of cervical spine. Methods From March 2016 to March 2017, 76 patients with hyperextension injury of cervical spine were treated in the second hospital affiliated to Wenzhou medical university. The patients were selected and randomly divided into two groups according to the random number table. The group A patients were underwent an internal fixation through anterior decompression and combined with celecoxib, eperisone hydrochloride, the group B were underwent anterior decompression and internal fixation only. The improvement of VAS score and ASIA neurological function score were observed preoperative and postoperative period at 4 and 24 weeks between the 2 groups. Results There was no significant difference in ASIA motor and sensory score between the two groups before treatment. The ASIA sensory score in group A was significantly higher than that in group B at 4 weeks and 24 weeks after operation (P<0.05). The VAS score in group A was significantly lower than that in group B at 4 weeks and 24 weeks after operation (P<0.05). Conclusion The combination of celecoxib, eperisone hydrochloride and internal fixation through anterior cervical decompression can improve the neurological function and alleviate the pain of the patients effectively, its clinical efficacy is remarkable.
hyperextension injury of cervical spinecelecoxibleperisone hydrochloric
NETL
NSTL
万方数据
维普
