首页|丙种球蛋白短程强化联合甲泼尼龙琥珀酸钠治疗小儿急重症脑炎的临床效果

丙种球蛋白短程强化联合甲泼尼龙琥珀酸钠治疗小儿急重症脑炎的临床效果

扫码查看
目的 探讨丙种球蛋白短程强化给药联合甲泼尼龙琥珀酸钠治疗小儿急重症脑炎的临床效果.方法 选取杭州市儿童医院2013年12月~2015年2月期间收治的88例急重症脑炎患儿,经随机数字表法均分为研究组(n=44)和对照组(n=44).对照组急重症脑炎患儿在常规治疗基础上加用甲泼尼龙琥珀酸钠,研究组急重症脑炎患儿在常规治疗基础上加用甲泼尼龙琥珀酸钠和丙种球蛋白短程强化给药.结果 研究组临床总有效率(88.64%)显著优于对照组(63.64%),数据对比差异有统计学意义(P<0.05).结论 应用常规治疗方案基础上,加用丙种球蛋白短程强化和甲泼尼龙琥珀酸钠可显著提高急重症脑炎患儿临床疗效.
Clinical effect of short strengthen gamma globulin combined with methylprednisolone sodium succinate in the treatment of infantile severe encephalitis
Objective To investigate the effect of short strengthen gamma globulin combined with methylprednisolone sodium succinate in treatment of children with acute severe encephalitis. Methods 88 children with severe encephalitis from December 2013 to February 2015 were randomly divided into the study group (n=44) and the control group (n=44). The control group of children with acute severe encephalitis were treated with methylprednisolone sodium succinate, study group of children with acute severe encephalitis were treated with methylprednisolone sodium succinate and gamma globulin to strengthen the administration of short. Results The total effective rate of the study group (88.64%) was significantly better than that of the control group (63.64%), and the difference was significant (P<0.05). Conclusion Based on the application of conventional therapy, gamma globulin combined with methylprednisolone sodium succinate for short-range enhancement can significantly improve the clinical curative effect of children with acute severe encephalitis.

childrenacute severe encephalitismethylprednisolone sodium succinateimmunoglobulinshort-range enhancement

邓青青、周杰林、贾黎红、杨明、李光乾

展开 >

杭州市儿童医院 儿内科,浙江 杭州 310000

小儿 急重症脑炎 甲泼尼龙琥珀酸钠 丙种球蛋白 短程强化

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(11)
  • 6